초유의 섭취가 최대 운동 시 Cortisol, Immunoglobulin, T-cell, NK-cell에 미치는 영향
Effect of Bovine Bolostrum Supplementation on Serum Cortisol, Immunoglobulin and T-cell, NK-cell during Maximal Exercise in Humans
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초록
본 연구는 건강한 남학생 7명을 대상으로 하여 7일 동안 초유를 섭취하게 하고 최대 운동을 실시하여 면역글로불린과 T-cell, NK-cell, 코티졸의 변화를 관찰하였다. 피험자는 K대에 재학 중인 체육을 전공하는 남학생 7인으로 하였다. 초유 섭취 전 트레드밀을 이용하여 점증부하방법으로 최대운동을 실시하였고, 7일간의 초유를 섭취한 후에 동일한 방법으로 운동을 실시하였다. 채혈은 안정 시와 운동 직후, 회복 15분, 30분에 전완 정맥에서 각각 10㎖를 채혈하였다. 채혈한 혈액으로부터 면역글로블린과 T-cell, B-cell, NK-cell, 코티졸의 변화를 관찰하였다. 그 결과 T-cell, B-cell, NK-cell, IgA, IgG, IgM. cortisol은 운동을 통한 채혈시점에서는 통계적으로 유의한 차이가 나타났다(p<.05). 그러나 T-cell, B-cell, NK-cell, 혈청 IgM, IgG, IgA는 초유 섭취 전과 후의 비교에서는 통계적으로 유의하게 나타나지 않았다. 코티졸의 농도는 초유의 섭취 전과 후의 비교에서 안정 시, 운동 직후, 회복 15분, 회복 30분에서 모두 유의한 차이를 나타내었다(p<.05). 결과적으로 초유 섭취 전과 섭취 후, 두 번의 측정에서 운동을 실시함으로써 면역 세포와 Ig, 코티졸은 유의한 차이를 나타내었으나, 초유 섭취 전과 섭취 후를 비교하였을 때 코티졸을 제외하고 Ig과 T-cell, B-cell, Nk-cell 에서는 유의한 차이를 나타내지 않았다. 따라서 초유의 7일간 섭취는 코티졸의 농도를 증가시키는 것으로 생각된다.
Abstract
The purpose of this study was to investigate the effect of 7days of bovine colostrum supplementation on immunoglobulin and T-cell, NK-cell during maximal exercise with 7 healthy males. Blood samples were taken before maximal exercise test, during maximal exercise test immediately after exercise, recovery 15, 30 minutes. Subjects were measured and compared with pre, and post- supplementation. Each experiment monitored and analyzed the change in immunoglobulin, T-cell, Nk-cell, cortisol. Serum IgM, IgG, IgA cortisol concentration were shown graded increase, each experiment were significantly increased in post-exercise (p<.05). Compared with pre, post-supplementation value were not significantly (p>.05), but cortisol concentration were different significantly (p<.05). B-cell, T-cell concentration were shown graded decreased, each experiment were significantly (p<.05). Compared with pre, post-supplementation value were not significantly. NK-cell concentration was graded increase, each experiment were significantly increase in post-exercise (p<.05). Compared with pre, post-supplementation value were not significantly. As the result, it was shown that bovine colostrum supplementation increased the cortisol level significantly.
참고문헌 (29)
- "홀스타 인 초유 whey fraction의 면역세포 활성화에 관한 연구", 34(4), pp.694~699 (2002)
- "고강도 지구성 운동이 흰쥐의 면역기능 에 미치는 영향" (2002), 고려대학교 대학원
- "The effects of bovine colostrum supplementation on body composition and exercise performance in active men and women", 17, pp.243~247 (2001)
- "Insulin in bovine colostrum and milk evolution throughout Lactation and binding to caseins", pp.4320~4325 (1991)
- "Stress hormones and the immunological responses to heat and exercise", 19(2), pp.130~143 (1998)
- "Effect of bovin colostrum on anaerobic exercise performance and plasma insulin-like growth factor I", 21, pp.577~588 (2003)
- "Some aspects of the acute phase response after a marathon race and the effects of glutamine supplementation", 75(1), pp.47~53 (1997)
- "Circulation monouclear cell numbers and function during intense exercise and recovery", pp.1089~1097 (1991)
- "Changes in blood leukocyte opulations induced by acute maximal and chronic submaximal exercise", pp.435~442 (1990)
- "Elite athlete immunology importance of nutrition", 21(1), pp.44~50 (2000)
- "Stress- induced suppression of the cellular immune reactions on the neuroendocrine control of the immune system", 46(6), pp.551~555 (1996)
- "Moculation of human humoral immune response through orally adimistred bovine colostrum", 3, pp.93~96 (2001)
- "Immune response to changes in training intensity and volume in runners", 27(8), pp.1111~1117 (1995)
- "Influence of acute submaximal exercise on T-lymphocyte suppressor cell function in health young men", 82, pp.151~154 (2000)
- "amajor immunoglobulin in most bovine external secretion", immu(l), pp.552~563 (1971)
- "Lymphocyte proliferation response after exercise in men", pp.179~185 (1991)
- "Decresased saliary immunoglobulins after intense interval exercise before and after training", pp.141~149 (1993)
- "Effect of eccentric exercise on the immune system in men", pp.461~468
- "The effect of exercise intensity and duration on salivary immunoglubulin A", pp.108~111 (1991)
- "and IgG responses to bovine colostrum supplementation during training", 93, pp.732~1 739 (2002)
- "Effect of bovin colostrum supplementation of serum IGF-I and saliva IgA during training", 83, pp.1144~1151 (1997)
- "Exercise-induced alterations in natural Killer cell number and function", 76(5), pp.485~491 (1996)
- "The olympic book of sports medicine", pp.635~645 (1988)
- "Effects of exercise training on response to central injection of CRF and noise stress", pp.93~98 (1991)
- "How physical exercise influence the influences the establishment of infections", 19(6), pp.393~400 (1995), & Bruunsgaard
- "Response of leukocyte and lymphocyte subs- ets during prolonged recovery" (1993)
- "Immunological effects of insulin-like growth factor-I enhancenment of immunoglobulin synthesis", immu(l) (1994)
- "Immunomodulation by 8-week voluntary exercise in mice", 168, pp.413~420 (2000)
- "Resistence training and immune function in elderly women", 27, pp.176~ (1995)