파워종목 선수들의 ACTN3 유전자 다형별 무산소성파워의 차이
The Difference of Anaerobic Power Based on Muslce Power Sports Athletes in ACTN3 Genotype
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초록
본 연구의 목적은 엘리트 파워지향성 선수들을 대상으로 ACTN3 유전자 다형의 분포 비율과 Wingate test를 통한 최대무산소성 수행능력과의 관련성을 비교하는 것이다. 근력 및 파워를 요하는 100명의 국가대표및 상비군 선수들(레슬링 31명, 유도 13명, 복싱 16명, 펜싱 6명, 사이클 16명, ≤400m 육상 18명)을 대상으로 ACTN3 유전자다형을 조사하였다. 무산소성 능력의 평가항목인 Wingate test를 통해 Peak power 및 Average power를 다형별로 비교하였다. 남자 선수들 체중 당 Peak Power(W/kg)에서 RR형+RX형이13.67 ± 1.57, XX형은 12.50 ± 2.04로 R allele를 가진 선수들에게서 유의하게 높게 나타났다(p<0.05). 그러나 여자 선수들에서는 모든 항목에서 아무런 차이가 보이지 않았다. 결론적으로, ACNT3 R allele를 보유한 남자 선수들에서 Peak power가 높을 것으로 사료된다
Abstract
The ACTN3 R577X polymorphism has been associated with an elite athletes status. Several studies have determined that the R allele is connected with power-oriented athletic performance, whereas the nonfunctional XX genotype may give some beneficial effect for endurance performance. The main aim of the study was to determine the possible interaction between the ACTN3 R577X polymorphism and an power-oriented athlete status in Korean elite athletes (wrestling 31, judo 13, boxing 16, fencing 6, cycle 16, ≤400m athlete 18). Each athletes performed a 30-second WAPtest with a resistance equal to 7.5% for male and 5% for female body weight. Genotyping for the ACTN3 R577X (rs1815739) polymorphism was performed using the TaqMan approach. The ACTN3 R577X genotypes exhibited a HardyWeinberg equilibrium distribution in our population. The relative and absolute average power results of the 30-second Wingate test did not differ significantly among the genotypes. However, the relative peak power result of the Wingate test was significantly higher in the R-allele- dominant model groups than in the XX group in male but not female athletes. These results suggest that the ACTN3 R allele is associated with the relative peak power during the Wingate test in male Korean elite athletes.
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