가속도계를 이용한 한국인들의 신체활동수준과 심혈관 대사 질환 요인 및 대사증후군과의 관계 : 2014-2016 국민건강영양조사를 활용하여
The Associations between Accelerometer-measured Physical Activity and Cardiometabolic Disease Risk Factors and Metabolic Syndrome in Korean Adults : Results from 2014-2016 KNHANES DATA
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초록
[목적] 본 연구의 목적은 2014-2016 국민건강영양조사 설문과 가속도계 자료를 활용하여, 한국 성인들의 신체활동수준과 심혈관 대사 질환 요인 및 대사증후군과의 관계를 분석 하는 것이다. [방법] 본 연구의 대상자는 설문조사에 응답하고, 가속도계 최소착용기준을 만족한 942명을 중강도·고강도 신체활동수준을 사분위수 범위를 이용하여 그룹화 하였으며, 대응-사례 대조 연구방법을 적용하고 각 그룹 당 80명씩 할당 하였다(N=320). 대상자의 일반적 특성은 성별, 연령, 교육수준, 가계소득수준, 흡연상태, 직업분류가 포함되었으며, 복부비만은 허리둘레와 내장지방지수, 심혈관 요인은 수축기 및 이완기 혈압, 평균동맥압과 ePWV를 이용하였다. 혈중지질대사위험은 총콜레스테롤, 당화혈색소, 공복혈당, 중성지방(TG), HDL-C요인을 분석하였고, 인슐린 저항성 대리지표는 TG/HDL-C을 이용하였다. 가속도계로 측정된 신체활동 수준에 따른 심혈관 대사질환요인의 차이를 분석하기 위해서 일원변량분석(one-way ANOVA)과 Boneferroni correction 사후검정을 적용하였으며, 다항 로지스틱 회귀분석을 이용하여 신체활동수준과 심혈관 대사질환 요인과 대사증후군과의 관계를 분석 하였다. 모든 통계에대한 유의수준은 p <.05로 하였다. [결과] 복부비만, 심혈관 및 혈중지질의 모든 요인은 그룹간 유의한 차이가 나타났으며(p <.05), 허리둘레, 수축기 및이완기 혈압과 평균 동맥압의 경우 신체활동 수준이 가장 낮은 하위 Q1 그룹은 Q3과 Q4 그룹보다 높았다(p <.01). 내장지방지수, 중성지방, TG/HDL-C의 경우, 신체활동 수준이 낮은 하위 Q1, Q2 그룹은 Q3과 Q4 보다 높았고(p <.01), HDL-C는 낮았다(p <.001). 허리둘레, 내장지방지수, 공복혈당, 중성지방, HDL-C, TG/HDL-C 및 대사증후군의 경우, MVPA가 가장 낮은 하위 Q1과 비교하여 Q3 그룹은 약 57%, Q4 그룹은 65% 이상 위험성이 감소하였다(p <.05). [결론] 높은 수준의 중강도·고강도 신체활동은 심혈관 대사 질환 요인과 대사증후군의 위험성을 감소시키는 것으로나타났다. 추후 연구에서는 신체활동 강도 또는 영역에 따른 심혈관 대사 질환 및 대사증후군의 관계를 살펴보는 연구가 필요할 것으로 생각된다.
Abstract
PURPOSE This study aimed to examine the associations between accelerometermeasured physical activity and both cardiometabolic disease risk factors and metabolic syndrome in Korean adults. METHODS We performed a retrospective cohort study with age-sex matched case-control using data from the 2014-2016 Korea National Health and Nutrition Examination Survey, which was administered to South Korean adults (n=320). Individuals were categorized into quartiles based on accelerometermeasured moderate-to-vigorous physical activity (MVPA). Demographic and physical characteristics, waist circumference, visceral adiposity index, blood pressure, lipid profiles, and TG/HDL-C were observed. The associations between MVPA status and cardiometabolic disease risk factors as well as metabolic syndrome were determined using multiple logistic regression. RESULTS For the waist circumference, SBP, DBP, MBP, visceral adiposity, triglyceride, and a surrogate estimate of insulin resistance, the Q1 and Q2 groups had higher means compared with the Q3 and Q4 groups. HDL-C was higher in the Q3 and Q4 groups compared to the Q1 and Q2 groups. Odds ratios for cardiometabolic disease risk factors and metabolic syndrome decreased in a curvilinear manner with the increasing quartile of MVPA. CONCLUSIONS Adults with higher MVPA participation were strongly associated with cardiometabolic disease risk factors and metabolic syndrome.
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