본문 바로가기
KERD
논문KCI 등재

黄褐斑发病机理研究进展

Progress on Pathogenesis of Melanosis

리려|맹홍|악립지|등소봉
한국피부과학연구원 (Korea Institute of Dermatological Sciences)|2016.12|아시안뷰티화장품학술지 (Asian Journal of Beauty and Cosmetology)|제14권 제4호|pp. 473-479|DOI 10.20402/ajbc.2016.0076

0

조회

0

다운로드

0

인용

0

참고문헌

키워드

黄褐斑病因发病机理内源性因素外源性因素황갈반병인발병 메커니즘내인성 요인외인성 요인
주제분류미용

초록

黄褐斑是一种临床常见的面部慢性皮肤色素代谢障碍性疾病，可影响患者的面部美观。为给黄褐斑的积极预防与治疗提供理论依据，本文对黄褐斑的形成机理进行了分析。调研了黄褐斑近年的研究进展，从内源性因素和外源性因素两个角度对黄褐斑的病因病机进行了归纳总结。内源性因素主要与遗传因素、内分泌、脂质过氧化、血管内皮功能、血液流变性、微量元素等有关。外源性因素主要与紫外线、皮肤微生态、使用化妆品不当等有关。黄褐斑的发病以内源性因素为主、外源性因素为辅。深入、全面地了解黄褐斑的发病机理可以对黄褐斑进行更积极有效的防治。

Abstract

Melanosis is a common clinical pigmentation disorder which affects patients’ facial aesthetics. This review describes the recent progress on mechanism of melanosis in order to provide the evidence for clinic therapy of melanosis. By investigating the recent progress of melanosis, we summarize the mechanism of melanosis from two aspects: endogenous and exogenous factors. Endogenous factors include genetic factors, endocrine, lipid peroxidation, endothelial function, blood rheology, trace elements and so on. Exogenous factors include ultraviolet (UV), skin microecology, improper use of cosmetics and so on. The pathogenesis of chloasma is given priority to endogenous factors. In depth and comprehensive understanding of the pathogenesis of chloasma contribute to the more effective prevention and treatment of chloasma.

참고문헌 (32)

  1. Bai J, "Discussion on microflora between healthy people and patient’s lesion with chloasma", Chinese Journal of Microecology, 18, pp.137~ (2006)
  2. Bai YQ, "The pathogenesis of chloasma", Chinese Archives of Traditional Chinese Medicine, 23, pp.2243~2244 (2005)
  3. Brianezi G, "Changes in nuclear morphology and chromatin texture of basal keratinocytes in melasma", Journal of the European Academy of Dermatology and Venereology, 29, pp.809~812 (2014)
  4. Chen ZW, "Effects of xiaoban meifu tang on nitric oxide and MDA in serum of patients with chloasma", Chinese Journal of Dermatovenerology of Integrated Traditional and Western Medicine, 13, pp.371~373 (2015)
  5. Cui ZJ, "Current research status of chloasma", Sichuan Medical Journal, 25, pp.116~118 (2004)
  6. He L, "New thought of diagnosis and treatment of chloasma", Journal of Dermatology and Venereology, 34, pp.13~14 (2012)
  7. Im S, "Increased expression of alpha-melanocyte-stimulating hormone in the lesional skin of melasma", British Journal of Dermatology, 146, pp.165~167 (2002)
  8. Javaheri SM, "Safety and efficacy of glycolic acid facial peel in Indian women with melasma", International Journal of Dermatology, 40, pp.354~357 (2001)
  9. Jian D, "Diethylstilbestrol enhances melanogenesis via cAMPPKA- mediating up-regulation of tyrosinase and MITF in mouse B16 melanoma cells", Steroids, 76, pp.1297~1304 (2011)
  10. 강희영, "What Should Be Considered in Treatment of Melasma", Annals of Dermatology, 22(4), pp.373~378 (2010), 대한피부과학회
  11. Kang HY, "Transcriptional profiling shows altered expression of wnt pathway– and lipid metabolism–related genes as well as melanogenesisrelated genes in melasma", Journal of Investigative Dermatology, 131, pp.1692~1700 (2011)
  12. Kang WH, "Melasma: histopathological characteristics in 56 Korean patients", British Journal of Dermatology, 146, pp.228~237 (2002)
  13. Kim EH, "The vascular characteristics of melasma", Journal of Dermatological Science, 46, pp.111~116 (2007)
  14. Kim NH, "H19 RNA downregulation stimulated melanogenesis in melasma", Pigment Cell & Melanoma Research, 23, pp.84~92 (2010)
  15. Kim NH, "Reduced MiR-675 in exosome in H19 RNA-related melanogenesis via MITF as a direct target", Journal of Investigative Dermatology, 134, pp.1075~1082 (2014)
  16. Lee AY, "Recent progress in melasma pathogenesis", Pigment Cell & Melanoma Research, 28, pp.648~660 (2015)
  17. , a new vasoconstrictor peptide, "British Journal of Clinical Pharmacology", 2004, 720~725
  18. Lin BZ, "The related research of traditional Chinese medicine between syndrome types and sex hormone levels in hyperplasia of mammary glands and chloasma", Fujian Journal of Traditional Chinese Medicine, 40, pp.54~55 (2009)
  19. Lin XY, "Test of nitric oxide and endothelin-1 levels in serum of patients with chloasma", Journal of Clinical Dermatology, 36, pp.562~ (2007)
  20. Liu Y, "Endothelin and skin diseases", Chinese Journal of Aesthetic Medicine, 21, pp.151~153 (2012)
  21. Ni LS, "Relationship between the traditional Chinese medicine chloasma type and trace elements in female", China Journal of Leprosy and Skin Diseases, 23, pp.531~532 (2007)
  22. Ohata C, "Expression of estrogen receptor β in normal skin, melanocytic nevi and malignant melanomas", The Journal of Dermatology, 35, pp.215~221 (2008)
  23. Passeron T, "Melasma pathogenesis and influencing factors – an overview of the latest research", Journal of the European Academy of Dermatology and Venereology, 27, pp.5~6 (2013)
  24. Shin J, "Repeated exposure of human fibroblasts to UVR induces secretion of stem cell factor and senescence", Journal of the European Academy of Dermatology and Venereology, 26, pp.1577~1580 (2012)
  25. Tang N, "The research status of chloasma etiology and pathogenesis", Journal of Diagnosis and Therapy on Dermato-venereology, 20, pp.302~304 (2013)
  26. Wang LL, "Effect of turbidity toxin and fumigation on nitric oxide and endothelin-1 in serum of patients with chloasma", Lishizhen Medicine and Materia Medica Research, 24, pp.351~352 (2013)
  27. Xie MF, "Effect of pearl four white cream on serum SOD and MDA of liver type chloasma", Chinese Medicine Modern Distance Education of China, 9, pp.30~31 (2011)
  28. Yuan MF, "Progress of chloasma etiology and pathogenesis", Clinical Journal of Traditional Chinese Medicine, 25, pp.81~83 (2013)
  29. Zhang GD, "Pathogenesis and treatment of chloasma", Fujian Medical Journal, 37, pp.128~130 (2015)
  30. Zhang HX, "Relevant study on chloasma and tyrosinase activity", Journal of Liaoning University of Traditional Chinese Medicine, 12, pp.99~100 (2010)
  31. Zhou M, "Damage of lipid peroxidation on cellular components", Medical Journal of Chinese People’s Liberation Army, 9, pp.145~147 (1984)
  32. Zou HC, "Etiology and pathogenesis of melasma", Journal of Dermatology and Venereology, 32, pp.27~29 (2010)

관련 논문AI추천

What Should Be Considered in Treatment of Melasma강희영, Jean-Paul Ortonne대한피부과학회 · Annals of Dermatology2010 · 제22권 제4호Plasma Metabolomics Indicates Potential Biomarkers and Abnormal Metabolic Pathways in Female Melasma PatientsHedan Yang, Hui Ding, Huiying Zheng, Lin Tong, Pingping Cai, Xiaojie Sun, Xiaoli Zhang, Xinyu Li, Yi Chen, Yin Yang, Yiping Ge대한피부과학회 · Annals of Dermatology2024 · 제36권 제5호以整体观诠释科学美白리리, 동은묘, 두탁(杜卓)한국피부과학연구원 · 아시안뷰티화장품학술지2016 · 제14권 제2호피부 광노화의 중의학적 메커니즘에 관한 탐구김효철, 오경동한국피부과학연구원 · 아시안뷰티화장품학술지2011 · 제9권 제4호基于ITA值的皮肤颜色影响因素分析맹홍, 역범, 동은묘, 왕시기, 허명량한국피부과학연구원 · 아시안뷰티화장품학술지2018 · 제16권 제4호Update on Melasma TreatmentsHwa Jung Ryu, Ju Young Jo, Su Ji Chae대한피부과학회 · Annals of Dermatology2024 · 제36권 제3호

이 간행물의 다른 논문 (12건)

대복피 추출물의 분획별 항균 및 항산화 활성이현화, 송선영pp. 359-368아로마 오일을 이용한 발 반사요법이 헤어 미용사의 스트레스 완화에 미치는 영향장윤선, 이순례, 김광옥, 심은경pp. 369-378안토시아닌 유무에 근거한 천연화장품의 소재로서 식용식물 추출물의 유용성 평가박두현, 김성희, 이은희pp. 379-388피부미용실에서 서비스요인과 관계품질이 고객행동의도에 미치는 영향김민정pp. 389-398JNK-AP1 기전을 통한 국화꽃 추출물의 MMP1 발현 변화 조절김영주pp. 399-405
원문 보기