플라보노이드 쿼세틴 함유 화장료의 피부개선 효과에 관한 연구
A Clinical Study of Flavonoid Quercetin-Containing Cosmetics on the Skin Improvement
1
조회
0
다운로드
6
인용
0
참고문헌
키워드
초록
The effects of flavonoid quercetin (ex: anti-oxidation, anti-cancer, anti-inflammatory and anti-allergy, etc.)have been confirmed through various studies, and it has been used as the ingredient of cosmetics. However,it’s been hard to find a study on its clinical trials in the skin. Therefore, this study has performed skin clinical trials after applying the quercetin-containing product to the skin and examined its skin improvement effects. According to the analysis, in terms of changes in skin pores, the number of pores on the face in the experimental group in which quercetin-containing cream was used decreased (p>.05). In terms of changes in pigmentation on the face, improvement of pigmentation was observed in the experimental group(p<.05). In terms of wrinkles, wrinkle improvement was observed in the experimental group (p>.05). In terms of skin tone,improvement of skin tone was detected in the experimental group (p<.05). Therefore, it appears that quercetin would improve skin tone and pigmentation as the improvement of anti-oxidation effects.
Abstract
The effects of flavonoid quercetin (ex: anti-oxidation, anti-cancer, anti-inflammatory and anti-allergy, etc.)have been confirmed through various studies, and it has been used as the ingredient of cosmetics. However,it’s been hard to find a study on its clinical trials in the skin. Therefore, this study has performed skin clinical trials after applying the quercetin-containing product to the skin and examined its skin improvement effects. According to the analysis, in terms of changes in skin pores, the number of pores on the face in the experimental group in which quercetin-containing cream was used decreased (p>.05). In terms of changes in pigmentation on the face, improvement of pigmentation was observed in the experimental group(p<.05). In terms of wrinkles, wrinkle improvement was observed in the experimental group (p>.05). In terms of skin tone,improvement of skin tone was detected in the experimental group (p<.05). Therefore, it appears that quercetin would improve skin tone and pigmentation as the improvement of anti-oxidation effects.
참고문헌 (25)
- 강영희, "생명과학 대사전" (2008), 아카데미서적
- 김선영, "쿼세틴의 피부 흡수 증진을 위한 세포 침투 펩타이드 부착 리포좀 시스템", 석사, 정밀화학과, pp.2012
- 김창수, "오존에 의한 피부 손상 확인 및 이를 방어하는 피부외용제 소재의 탐색", 대한화장품학회지, 30, pp.39~49 (2004)
- 김해경, "HPLC-이중질량분석법을 이용한 9 품종의 감귤 플라보노이드 성분과 생물학적 활성 분석", 석사, 화학, pp.2011
- 배인순, "황백 열수추출물의 피부노화 억제 효과 및 화장품 소재 활용에 관한 연구", 박사, 공중보건학, pp.2009
- 유민정, "하고초 추출물의 두피 보호 효과에 관한 연구", 대한피부미용학회지, 8(4), pp.157~170 (2010), 대한피부미용학회
- 유민정, "향나무 추출물의 항균, 항산화 및 각질세포 보호 효과", 대한피부미용학회지, 8(2), pp.107~116 (2010), 대한피부미용학회
- 윤규형, "식물성 미백소재를 이용한 기능성 화장품의 개발동향 분석 및 제품화 연구", 석사, 향장품학, pp.2003
- 이진아, "마황근과 화피 추출물의 국소 도포에 따른 피부주름의 변화에 관한 연구", 대한피부과학회지, 42(11), pp.1396~1405 (2004), 대한피부과학회
- 이홍금, "해양으로부터의 기능성 화장품 소재 개발 동향", 대한화장품학회, 27, pp.37~42 (2001)
- 이희경, "비타민나무 열매로부터 분리한 Quercetin 3-glucoside-7-rhamnoside 의 항산화 및 주름개선 효과", 대한피부미용학회지, 10(3), pp.731~736 (2012), 대한피부미용학회
- 윤규형, "식물성 미백소재를 이용한 기능성 화장품의 개발동향 분석 및 제품화 연구", 석사, 향장품학, pp.2003
- 정숙자, "Flavonoids의 생리 활성 기능에 관한 고찰", 석사, 식품제조관리, pp.2004
- 조춘구, "Antioxidative and Antimicrobial Effects to Skin Flora of Extracts from Peel of Allium cepa L.", 대한피부미용학회지, 8(3), pp.49~58 (2010), 대한피부미용학회
- 2012년 화장품산업분석 보고서, "한국보건산업진흥원", ~ (2012)
- 홍미선, "인간 진피 섬유아세포에서 천연성분 쿼세틴의 작용기전", 대한피부미용학회지, 10(3), pp.571~579 (2012), 대한피부미용학회
- Cho SY, "Quercetin suppresses proinflammatory cytokines production through MAP kinases and NF-kB pathway in lipopolysaccharide-stimulated macrophage", Mol. Cell. Biochem, 243, pp.153~160 (2003)
- 김석창, "황금으로부터 항산화 활성 성분의 분리", 한국약용작물학회지, 14(4), pp.212~216 (2006), 한국약용작물학회
- 김경동, "약용식물의 부위별 및 추출용매에 따른 효능 연구", 대한화장품학회지, 33(2), pp.127~135 (2007), 대한화장품학회
- Kim MJ, "Anti- Wrinkle effect of safflower (Carthamus tinctorius L.) seed extract (Ⅱ)", J. Soc. Cos. Sci. Kor, 30, pp.449~456 (2004)
- Lee KT, "The study on the anti-aging effects of Mallotus japonicus bark extracts", J. Soc. Cos. Sci. Kor, 30, pp.445~448 (2004)
- Matsushima M, "Heme oxygenase-1 mediates the anti-allergic actions of quercetin in rodent mast cells", Inflamm. Res, 58, pp.705~715 (2009)
- Verma AK, "Inhibition of 7, 12-dimethylbenz(a)anthracene-and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin", Cancer Res, 48, pp.5754~5758 (1988)
- 대한화장품협회, "화장품 생산 실적 자료", ~
- "Datamonitor Personal Care Market Date", ~ (2012)