36-49岁北京地区女性皮肤皱纹与皮肤生理参数的关系
Research on the Relationship between the Skin Biophysical Parameters versus Wrinkles of 36–49 Years Old Beijing Female
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目的: 皮肤生理参数能够揭示皮肤皱纹状况。本研究旨在探讨36–49岁北京女性皮肤各生理参数与皱纹之间的关系。 方 法: 选取北京市55名健康女性（年龄36–49岁）为研究对象，测定左脸颊二十一个皮肤生理参数如皮肤的水合作用、经 皮水分流失（transepidermal water loss, TEWL）、皮脂含量、黑色素指数（sebum, melanin index, MI）、红色素指数 （erythema index, EI）、皮肤颜色、皮肤光泽、pH值、经皮氧分压（transcutaneous oxygen tension, pO2）、经皮二氧 化碳分压（transcutaneous carbon dioxide tension, pCO2）、皮肤温度、血液灌流量、皮肤弹性及皮肤纹理，分析了各 皮肤生理参数与皮肤弹性、纹理的相关性关系。 结果: 皮肤各生理参数与皮肤弹性、皮肤纹理有一定相关性。（1）皮肤 弹性参数R2、R5、R7与和皮肤光泽度之间有显著的正相关（p<0.01）。皮肤温度与R5成显著正相关（p<0.01）。皮肤 pO2与R7成显著正相关（p<0.01）。皮肤弹性和pH值却呈负相关关系。（2） 皮肤纹理Rz和A之间存在显著的正相关关系 （p<0.01）。皮肤纹理Ra、Rp与和EI也具有显著正相关关系（p<0.01）。 结论: 各皮肤生理参数和皱纹之间的相关性表 明，年龄是影响皮肤光泽度，皮肤温度和氧分压的降低，皮肤pH，EI和皮肤颜色的上升的重要因素。
Abstract
Purpose: Skin biophysical parameters reveal skin condition of wrinkle. This study aimed to explore the variation of skin condition with wrinkles of 36–49 years old Beijing female. Methods: 55 healthy females (age ranged from 36 to 49 years old) coming from Beijing city were chosen for this study. We measured twenty one skin biophysical parameters such as skin hydration, transepidermal water loss (TEWL), sebum, melanin index (MI), erythema index (EI), skin shades, skin radiance, pH, transcutaneous oxygen tension (pO2), transcutaneous carbon dioxide tension (pCO2), skin temperature, blood perfusion, skin elasticity and skin texture in left cheek, and compared correlation between other parameters and elasticity and texture. Results: There were some correlations between skin biophysical parameters and skin elasticity and skin texture: (1) There were signifiant positive correlation (p<0.01) between skin elasticity parameters, R2, R5, R7, and skin radiance. Skin temperature was signifiantly (p<0.01) correlated with R5 positively. pO2 was signifiantly (p<0.01) correlated with R7 positively. There were negative correlation between three skin elasticity and pH. (2) There were signifiant positive correlation (p<0.01) between skin texture, Rz, and A. There were signifiant positive correlation (p<0.01) between two of skin texture, Ra, Rp, and EI. Conclusion: The correlations shown between the skin biophysical parameters and wrinkle factors demonstrate that the decrease of skin radiance, skin temperature and pO2, increase of skin pH, EI and skin shades A are affected by aging factors.
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