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Understanding SARS-CoV-2 Variants and Safety Countermeasures for the Fight against Omicron

홍복실|김명류
동북아학술저널연합 (Northeast Asian Studies Journal Institute (J-INSTITUTE))|2022.03|International Journal of Crisis & Safety|제7권 제1호|pp. 1-12

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참고문헌

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VaccinationDeltaSARS-CoV-2 VariantsOmicronSafety Countermeasures
주제분류기타사회과학

초록

Purpose: This study examines the mutation profiles and global prevalence of SARS-Cov-2 variants. We further investigate the viral characteristics of the Delta and Omicron variants, such as epidemiology and transmissibility, disease severity, immune escape and vaccine effectiveness. Moreover, safety countermeasures for the fight against the Omicron variant are explored regarding the new pandemic response strategies focused on medical response and COVID-19 guidelines for quarantine rules. Method: This study was conducted on Web-based searches about the latest updates COVID-19 from the World Health Organization, Korea Centers for Disease Control and Prevention, and the Ministry of Food and Drug Safety. In addition, we searched for the ‘SARS-CoV-2 variant”, and “COVID-19 and Delta, or Omicron” in PubMed and then reviewed the selected articles regarding variants of concern, the Delta and Omicron variants. Results: To date, there are five variants of concern available on the WHO tracking SARS-CoV-2 variants website. The Delta and Omicron variants are of particular concern among variants, and the Omicron variant is rapidly out-pacing the Delta variant worldwide to become the dominant circulating variant with a substantial growth ad-vantage having a shorter doubling time. Even though the Omicron variant has shown moderate and lower disease severity than the Delta variant, there is concern about the high possibility of immune evasion, and it is predicted to be the most prevalent variant in the Republic of Korea near future. Therefore, safety countermeasures to contain the spread of the Omicron variant will be implemented for gradual recovery to a new normal life. Conclusion: Accordingly, along with the domestic efforts such as encouraging third booster vaccination and maintaining high-level quarantine systems, international collaboration, clear and transparent communications, and even achievement of 70% coverage with COVID-19 vaccines in all countries will be necessary to battle against the SARS-CoV-2 variants and to stop the continuous prevalence of Omicron worldwide.

Abstract

Purpose: This study examines the mutation profiles and global prevalence of SARS-Cov-2 variants. We further investigate the viral characteristics of the Delta and Omicron variants, such as epidemiology and transmissibility, disease severity, immune escape and vaccine effectiveness. Moreover, safety countermeasures for the fight against the Omicron variant are explored regarding the new pandemic response strategies focused on medical response and COVID-19 guidelines for quarantine rules. Method: This study was conducted on Web-based searches about the latest updates COVID-19 from the World Health Organization, Korea Centers for Disease Control and Prevention, and the Ministry of Food and Drug Safety. In addition, we searched for the ‘SARS-CoV-2 variant”, and “COVID-19 and Delta, or Omicron” in PubMed and then reviewed the selected articles regarding variants of concern, the Delta and Omicron variants. Results: To date, there are five variants of concern available on the WHO tracking SARS-CoV-2 variants website. The Delta and Omicron variants are of particular concern among variants, and the Omicron variant is rapidly out-pacing the Delta variant worldwide to become the dominant circulating variant with a substantial growth ad-vantage having a shorter doubling time. Even though the Omicron variant has shown moderate and lower disease severity than the Delta variant, there is concern about the high possibility of immune evasion, and it is predicted to be the most prevalent variant in the Republic of Korea near future. Therefore, safety countermeasures to contain the spread of the Omicron variant will be implemented for gradual recovery to a new normal life. Conclusion: Accordingly, along with the domestic efforts such as encouraging third booster vaccination and maintaining high-level quarantine systems, international collaboration, clear and transparent communications, and even achievement of 70% coverage with COVID-19 vaccines in all countries will be necessary to battle against the SARS-CoV-2 variants and to stop the continuous prevalence of Omicron worldwide.

참고문헌 (48)

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관련 논문AI추천

SARS-CoV-2 Omicron Variant of Concern: Everything You Wanted to Know about Omicron but Were Afraid to Ask최준용, Davey M. Smith, Dong Hoon Shin연세대학교의과대학 · Yonsei Medical Journal2022 · 제63권 제11호SARS-CoV-2 Variants of Concern최준용, Davey M. Smith연세대학교의과대학 · Yonsei Medical Journal2021 · 제62권 제11호Current Status of COVID-19 Outbreak and Vaccination in the Republic of Korea김명류, 홍복실, Jueun Kwon동북아학술저널연합 · International Journal of Crisis & Safety2021 · 제6권 제3호SARS-CoV-2 Omicron Mutation Is Faster than the Chase: Multiple Mutations on Spike/ACE2 Interaction Residues김수현, 송창선, 전현정, Choi Yang Kyu, Kim Byoungguk, Kim Sinae, Kim Sung-Han, Kim Yong-Gil, Lee Youngmin, Netea Mihai, Nguyen Tam T., Park Ho-Young, Shin Kyeong-Cheol, Song Eun Young, Taitt Afeisha S., Yeom Su Cheong, Yum Hokee대한면역학회 · Immune Network2021 · 제21권 제6호SARS-CoV-2 Delta (B.1.617.2) Variant: A Unique T478K Mutation in Receptor Binding Motif (RBM) of Spike Gene김수현, 박호영, 송창선, 전현정, Hisham Yasmin대한면역학회 · Immune Network2021 · 제21권 제5호Rapid Emergence of the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 in KoreaKim Eun-Jin, Kim Heui Man, Kim Il-Hwan, Kim Jeong-Ah, Lee Chae Young, Lee Hyeokjin, Lee Jaehee, Lee Nam-Joo, Park Ae Kyung, Rhee JeeEun, Woo SangHee, Yoo Cheon-Kwon대한진단검사의학회 · Annals of Laboratory Medicine2023 · 제43권 제2호

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