수송나물(Salsola komarovii)의 항산화, 항염 및 미백 활성
The Antioxidation Effect of Salsola komarovii Extract and Its Influence on Cell Bio activity
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초록
수송나물은 동아시아에서 자생하는 염생식물로 바닷가와 같은 염분이 많은 토지에서도 생장이 가능한 식물이다. 전통적으로 수송나물은 식품으로서 사용되는 동시에 약용으로도 사용되었다. 본 연구는 수송나물의 화장품 원료로서의 가능성을 알아보기 위하여, 항산화 실험 및 세포실험을 실시하였다. 항산화능 측정을 위해 수송나물을 70% 에탄올로 추출물을 제조하였다. 항산화 측정에는 DPPH와 ABTS 법을 사용하였으며, 그 결과 각각의 실험에서 IC50값이 186.10 mg/mL과 121.89 mg/mL로 나타났다. 동시에 폴리페놀 함량과 환원능 측정을 실시하였고, 그 결과 22.5%의 폴리페놀 함량과 28.4%의 환원능이 나타났다. 세포실험에서는 MTT 법을 사용하여 해당 추출물이 세포독성이 없음을 나타내었으며, 100 μg/mL 농도에서 항염능과 미백능을 나타내었다. 결과적으로 수송나물 추출물은 미백 및 항염능을 가진 화장품 소재로서 사용가능함을 확인하였다.
Abstract
S. komarovii is halophyte that grows in soil or waters of high salinity, such as in saline semi-deserts, sloughs and seashores. Traditionally, S. komarovii has been used for food and medicinal purposes in Korea. S. komarovii was extracted in 70% ethanol to measure anti-oxidative activity using DPPH and ABTS assay. The IC50 values of the S. komarovii extract against DPPH radicals and ABTS radicals were 186.10 mg/mL and 121.89 mg/mL. In addition, total polyphenol and reducing power were measured. The S. komarovii extract exhibited superior polyphenolic (22.5%) and antioxidant (28.4%) contents. Regarding cell bioactivity, MTT assay was conducted to reveal cytotoxicity of S. komarovii extract and showed the non-cytotoxicity of S. komarovii extract. Anti-inflammatory and skin whitening effects were measured at 100 μg/mL. Therefore, this study suggests that the S. komarovii extract can be used as a functional cosmetic product material.
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