감마선으로 조사된 고욤잎, 감잎 및 뽕잎 복합추출물의 UV 조사 손상피부에 대한 개선 효과
Improvement Effect of Gamma-Irradiated Complex Leaf Extract of Date Plum, Persimmon and Mulberry on UVB-Induced Skin Damage
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초록
This study was conducted to evaluate the improvement effect of gamma-irradiated complex leaf extract of Date Plum, Persimmon and Mulberry (γ-DPME) on UVB induced skin damage. The samples were gamma irradiated at doses of 10 kGy. γ-DPME treatment tended to decrease UVB-induced immune cell infiltration and erthyderma index than the groups treated with non-gamma-irradiated DPME (n-DPME) and L-ascobic acid (AA). In addition, γ-DPME treatment significantly decreased skin thickness, melanin index and mast cell infiltration in UVB-irradiated skin. Moreover, γ-DPME treatment significantly decreased the compound 48/80-induced scratching behavior and immune cell infiltration than n-DPME group. These results show that gamma irradiation can be used to increase the physiological activities of DPME.
Abstract
This study was conducted to evaluate the improvement effect of gamma-irradiated complex leaf extract of Date Plum, Persimmon and Mulberry (γ-DPME) on UVB induced skin damage. The samples were gamma irradiated at doses of 10 kGy. γ-DPME treatment tended to decrease UVB-induced immune cell infiltration and erthyderma index than the groups treated with non-gamma-irradiated DPME (n-DPME) and L-ascobic acid (AA). In addition, γ-DPME treatment significantly decreased skin thickness, melanin index and mast cell infiltration in UVB-irradiated skin. Moreover, γ-DPME treatment significantly decreased the compound 48/80-induced scratching behavior and immune cell infiltration than n-DPME group. These results show that gamma irradiation can be used to increase the physiological activities of DPME.
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