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Parathyroid Hormone 1-34(Teriparatide) Treatment in Pelvic Insufficiency Fractures - A Report of Two Cases -

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As a result of aging population, the incidence of pelvic insufficiency fracture has been increasing. Pain-related immobility caused by pelvic insufficiency fractures may result in a serious dependency and high mortality with preexisting comorbidities. We present two cases of pelvic insufficiency fracture in elderly patients which had good clinical outcome by parathyroid hormone 1-34(teriparatide) treatment as well as a literature review.

Abstract

As a result of aging population, the incidence of pelvic insufficiency fracture has been increasing. Pain-related immobility caused by pelvic insufficiency fractures may result in a serious dependency and high mortality with preexisting comorbidities. We present two cases of pelvic insufficiency fracture in elderly patients which had good clinical outcome by parathyroid hormone 1-34(teriparatide) treatment as well as a literature review.

참고문헌 (10)

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  2. Kannus P, "Osteoporotic pelvic fractures in elderly women", Osteoporos Int, 16, pp.1304~1305 (2005)
  3. Krappinger D, "Low-energy osteoporotic pelvic fractures", Arch Orthop Trauma Surg, 130, pp.1167~1175 (2010)
  4. Peichl P, "Parathyroid hormone 1-84 accelerates fracture-healing in pubic bones of elderly osteoporotic women", J Bone Joint Surg Am, 93, pp.1583~1587 (2011)
  5. Beall DP, "Percutaneous augmentation of the superior pubic ramus with polymethyl methacrylate: treatment of acute traumatic and chronic insufficiency fractures", Skeletal Radiol, 36, pp.979~983 (2007)
  6. Buffum MD, "Cognitive impairment and pain management: review of issues and challenges", J Rehabil Res Dev, 44, pp.315~330 (2007)
  7. Thomas EN, "Osteoporotic fracture of the sacrum: sacroplasty and physical medecine", Ann Phys Rehabil Med, 52, pp.427~435 (2009)
  8. Alkhiary YM, "Enhancement of experimental fracture-healing by systemic administration of recombinant human parathyroid hormone (PTH 1-34)", J Bone Joint Surg Am, 87, pp.731~741 (2005)
  9. Andreassen TT, "Increases in callus formation and mechanical strength of healing fractures in old rats treated with parathyroid hormone", Acta Orthop Scand, 72, pp.304~307 (2001)
  10. Weber M, "Insufficiency fractures of the sacrum. Twenty cases and review of the literature", Spine (Phila Pa 1976), 18, pp.2507~2512 (1993)

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