코로나바이러스감염증-19 사회적 거리두기 중 온열처치가 면역노화 억제에 미치는 효과
Effects of thermotherapy on immunosenescence suppression during COVID-19 social distancing
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본 연구의 목적은 온열처치(반신침수, 42±0.5°C, 60분, 5분 간격)가 중년 폐경기 비만 여성(연령; 52.24±3.92세, 신장; 160.2±3.67cm, 체중; 62.34±5.13kg, 체지방율; 33.54±4.12%)의 면역노화 억제에 미치는 효과를 확인하는 것이다. 온열처치 전 후 심부체온, 림프구와 호중구의 수준을 비교하였으며, 연구 결과는 다음과 같다. 온열처치를 적용한 결과 심부체온은 유의하게 증가하였다(***p<0.001). 운동면역학 측면에서 중요한 림프구 수준도 온열처치 이후 유의하게 증가하였다(**p<0.01). 또한 면역노화와 관련성이 높은 호중구 역시 유의하게 증가하였다(**p<0.01). 결론적으로 온열처치는 심부체온을 상승시킴으로써 면역노화를 억제시키는데 효과가 나타난다는 사실을 확인하였다. 나아가 감염성 질환에 대한 저항력도 증가할 수 있을 것으로 판단된다. 차후 면역노화에 대한 억제력을 유발시키는 최적의 심부체온 범위와 자극에 대한 연구의 필요성을 제안한다.
Abstract
The purpose of this study was to undergo thermotherapy (half-body immersion, 42±0.5°C, 60 minutes, 5 minutes intervals) in middle-aged menopausal obese women (age; 52.24±3.92 years, height; 160.2±3.67cm, weight; 62.34±5.13kg, %body fat; 33.54±4.12%) on the suppression of immunosenescence. Pre and Post thermotherapy, the levels of tympanic temperature (Tty), lymphocytes, and neutrophil were compared. The results of the study are as follows, Tty was significantly increased (***p<0.001). Lymphocytes and neutrophils levels were significantly increased after thermotherapy (**p<0.01). In conclusion, thermotherapy is effective in suppressing immunosenescence by raising core temperature. Furthermore, it is believed that resistance to infectious diseases can be increased. Therefore, we propose the necessity of research on the optimal range of core temperature to immunosenescence.
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