얼굴 양쪽마비 및 척수염을 동반한 신경사르코이드증 환자 1예
A Case of Neurosarcoidosis Presenting with Facial Diplegia and Myelitis
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Background & Significance: Neurosarcoidosis is a chronic, multisystem, granulomatous, inflammatory disease of unknown etiology in the nervous system. Neurologic complications of sarcoidosis occur in approximately 5% of patients. Case: A 58-year-old woman was admitted with fever, chest tightness and urinary incontinence. On the neurological examination, bilateral peripheral type facial palsy and paresthesia between T2 and L1 level were noted. Electrophysiological studies showed normal nerve conduction velocities and normal sensory evoked potentials. Cerebrospinal fluid study showed mild pleocytosis and an increased amount of protein. There were normal levels of angiotensin converting enzyme and negative oligoclonal bands. Whole body positron emission tomography revealed focal uptakes at the right hilum, right lower paratrachea area and subcarina. In the thoracoscopic biopsy of hilar lymph node, small granulomatous inflammation without caseation necrosis was reported. Conclusions and Comments: We report a case of neurosarcoidosis manifestated by facial diplegia and myelitis verified by thoracoscopic mediastinal biopsy.
Abstract
Background & Significance: Neurosarcoidosis is a chronic, multisystem, granulomatous, inflammatory disease of unknown etiology in the nervous system. Neurologic complications of sarcoidosis occur in approximately 5% of patients. Case: A 58-year-old woman was admitted with fever, chest tightness and urinary incontinence. On the neurological examination, bilateral peripheral type facial palsy and paresthesia between T2 and L1 level were noted. Electrophysiological studies showed normal nerve conduction velocities and normal sensory evoked potentials. Cerebrospinal fluid study showed mild pleocytosis and an increased amount of protein. There were normal levels of angiotensin converting enzyme and negative oligoclonal bands. Whole body positron emission tomography revealed focal uptakes at the right hilum, right lower paratrachea area and subcarina. In the thoracoscopic biopsy of hilar lymph node, small granulomatous inflammation without caseation necrosis was reported. Conclusions and Comments: We report a case of neurosarcoidosis manifestated by facial diplegia and myelitis verified by thoracoscopic mediastinal biopsy.
참고문헌 (7)
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