사르코이드증에 의한 일측 성대 마비 1예
A Case of Unilateral Vocal Fold Paralysis Secondary to Sarcoidosis
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Vocal fold paralysis secondary to sarcoidosis is extremely rare but it can develop as a result of compressive lymphadenopathy, granulomatous infiltration, and neural involvement. We report the case of a 56-year-old woman who presented with unilateral vocal fold paralysis and enlarged supraclavicular lymph nodes. Computed tomography of the neck revealed multiple, enlarged, and matted lymph nodes at the cervical level of IV. An ultrasound-guided core needle biopsy of the lymph node was performed, and a histopathological diagnosis of sarcoidosis was made by validating the presence of noncaseating granuloma. After implementation of steroid therapy, the patient exhibited immediate recovery from vocal fold paralysis. Although an extremely rare disease, sarcoidosis should be included in the differential diagnosis of vocal fold paralysis. Accurate diagnosis and prompt steroid treatment may reduce the morbidity of patients with vocal fold paralysis secondary to sarcoidosis.
Abstract
Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Vocal fold paralysis secondary to sarcoidosis is extremely rare but it can develop as a result of compressive lymphadenopathy, granulomatous infiltration, and neural involvement. We report the case of a 56-year-old woman who presented with unilateral vocal fold paralysis and enlarged supraclavicular lymph nodes. Computed tomography of the neck revealed multiple, enlarged, and matted lymph nodes at the cervical level of IV. An ultrasound-guided core needle biopsy of the lymph node was performed, and a histopathological diagnosis of sarcoidosis was made by validating the presence of noncaseating granuloma. After implementation of steroid therapy, the patient exhibited immediate recovery from vocal fold paralysis. Although an extremely rare disease, sarcoidosis should be included in the differential diagnosis of vocal fold paralysis. Accurate diagnosis and prompt steroid treatment may reduce the morbidity of patients with vocal fold paralysis secondary to sarcoidosis.
참고문헌 (15)
- Valeyre D, "Sarcoidosis", Lancet, 383(9923), pp.1155~1167 (2014)
- Stager SV., "Vocal fold paresis: etiology, clinical diagnosis and clinical management", Curr Opin Otolaryngol Head Neck Surg, 22(6), pp.444~449 (2014)
- Coffey CS, "Sarcoidosis presenting as bilateral vocal cord paralysis from bilateral compression of the recurrent laryngeal nerves from thoracic adenopathy", J Voice, 23(5), pp.631~634 (2009)
- S. Mastan, "A rare manifestation of a multisystemic disease: a case of vocal cord palsy secondary to sarcoidosis", Case Reports, 2015(apr26 1), pp.bcr2015209728~bcr2015209728 (2015), BMJ[DOI]
- Jaffe R, "Vocal cord paralysis as the presenting symptom of sarcoidosis", Respir Med, 88(8), pp.633~636 (1994)
- Hintze JM, "Sarcoidosis presenting as bilateral vocal fold immobility", J Voice, 32(3), pp.359~362 (2018)
- 이희정, "폐문부의 림프절 종대 1예", Tuberculosis and Respiratory Diseases, 59(2), pp.209~212 (2005), 대한결핵및호흡기학회
- Miliauskas S, "Sarcoidosis–moving to the new standard of diagnosis?", Medicina (Kaunas), 46(7), pp.443~446 (2010)
- Baughman RP, "Clinical characteristics of patients in a case control study of sarcoidosis", Am J Respir Crit Care Med, 164(10), pp.1885~1889 (2001)
- Rizzato G, "Unusual presentation of sarcoidosis", Respiration, 72(1), pp.3~6 (2005)
- McLaughlin RB, "Laryngeal sarcoidosis presenting as an isolated submucosal vocal fold mass", J Voice, 13(2), pp.240~245 (1999)
- Alon EE, "Neurosarcoidosis affecting the vagus nerve", Ann Otol Rhinol Laryngol, 119(9), pp.641~645 (2010)
- Dean CM, "Laryngeal sarcoidosis", J Voice, 16(2), pp.283~288 (2002)
- Wijsenbeek MS, "Treatment of sarcoidosis", Clin Chest Med, 36(4), pp.751~767 (2015)
- James JC, "Treatment of laryngeal sarcoidosis with CO2 laser and mitomycin-C", Otolaryngol Head Neck Surg, 130(2), pp.262~264 (2004)