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논문KCI 등재

만성 이식편대숙주질환과 연관되어 발생한 다발성 근염

Polymyositis Related with Chronic Graft-Versus-Host Disease

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초록

Polymyositis is a rare manifestation of chronic graft-versus-host disease (GVHD) characterized by muscle pain, weakness, and an increased in muscle related enzymes. We report the case of a 23-year-old woman who presented polymyositis, related to a chronic GVHD following interruption of immunosuppressive treatment. It occurred 9 months after allogenic bone marrow transplantation from matched unrelated donor in the patient with acute myeloid leukemia (AML). The polymyositis responded rapidly to high dose prednisolone.

Abstract

Polymyositis is a rare manifestation of chronic graft-versus-host disease (GVHD) characterized by muscle pain, weakness, and an increased in muscle related enzymes. We report the case of a 23-year-old woman who presented polymyositis, related to a chronic GVHD following interruption of immunosuppressive treatment. It occurred 9 months after allogenic bone marrow transplantation from matched unrelated donor in the patient with acute myeloid leukemia (AML). The polymyositis responded rapidly to high dose prednisolone.

참고문헌 (9)

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  8. Couriel DR, "Chronic graft-versus-host disease manifesting as polymyositis: an uncommon presentation.", Bone Marrow Transplant, 30, pp.543~546 (2002)
  9. Stephenson AL, "Myositis associated graft-versus-host-disease presenting as respiratory muscle weakness", Thorax, 56, pp.82~84 (2001)

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