Parvimonas micra 뇌고름집 1예
A Case of Brain Abscess due to Parvimonas micra
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초록
Parvimonas micra는 아포비형성 혐기성 그람양성알균으로서 사람의 피부와 질, 점막에 상재균으로 존재하고, 기회감염을 일으키며 치과 치료 후에 심내막염이나 뇌고름집을 유발할 수 있다. 49세 여자 환자가 20일 전부터 발생한 열과 두통을 주소로 입원하였다. 환자는 열이 발생하기 직전 치아주위조직염을 진단 받아 치료받은 병력이 있었다. 뇌전산화단층촬 영술에서 우측측두엽에 고름집이 발견되어 ceftriaxone, isepamicin, metronidazole 병합요법을 시행하였고, 다음 날 수술을 통하여 뇌고름집을 흡인하고 폐쇄식배출을 시행하였다. 뇌고름집 혐기성 배양에서 분리된 균종은 상품화된 동정법과 16S rRNA 염기서열 분석에서 P. micra로 최종 동정되었다.
Abstract
Parvimonas micra is a non-spore-forming anaerobic gram-positive coccus, widely distributed as normal flora in the skin, vagina and mucosa, and able to cause opportunistic infections, particularly endocarditis and brain abscess following dental manipulations. A 49-year-old woman was hospitalized due to fever and headache. She had been diagnosed with periodontitis at the beginning of fever. A brain abscess was noted in the right temporal lobe on the brain CT, and she was treated with ceftriaxone, isepamicin and metronidazole. In the next day, abscess was aspirated and drained by a surgical procedure. An organism was isolated from an anaerobic culture of the abscess aspirate, and was identified as P. micra by a commercial kit and 16S rRNA sequencing.
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