Mycobacterium intracellurare에 의한 뇌농양 1예
A Case of Bain Abscess caused by Mycobacterium intracellurare
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Mycobacterium avium intracellulare complex (MAC) usually causes an opportunistic pulmonary infection in immunocompromised hosts who have underlying structural lung disease. Central nervous system infection due to MAC is very rare even in an immunocompromised host. Most previous reports of central nervous system infection due to MAC have been meningoencephalitis in patients infected with human immunodeficiency virus (HIV). Only four cases of brain abscess due to MAC have been reported worldwide. We report a case of brain abscess due to MAC in a non-HIV patient. Although drugs used for treatment of MAC have limited central nervous penetration, an azithromycin-based antituberculous therapy after surgical drainage of the abscess showed improvement. To the best of our knowledge, this is the first reported case of MAC brain abscess in the Korean literature. Key Words: Mycobacterium
Abstract
Mycobacterium avium intracellulare complex (MAC) usually causes an opportunistic pulmonary infection in immunocompromised hosts who have underlying structural lung disease. Central nervous system infection due to MAC is very rare even in an immunocompromised host. Most previous reports of central nervous system infection due to MAC have been meningoencephalitis in patients infected with human immunodeficiency virus (HIV). Only four cases of brain abscess due to MAC have been reported worldwide. We report a case of brain abscess due to MAC in a non-HIV patient. Although drugs used for treatment of MAC have limited central nervous penetration, an azithromycin-based antituberculous therapy after surgical drainage of the abscess showed improvement. To the best of our knowledge, this is the first reported case of MAC brain abscess in the Korean literature. Key Words: Mycobacterium
참고문헌 (20)
- Koh WJ, "Diagnosis and treatment of nontuberculous mycobacterial lung disease", Korean J Med, 74, pp.120~131 (2008)
- Uldry PA, "Chronic Mycobacterium avium complex infection of the central nervous system in a nonimmunosuppressed woman", Eur Neurol, 32, pp.285~288 (1992)
- Murray R, "Cerebral mycobacterium avium infection in an HIV-infected patient following immune reconstitution and cessation of therapy for disseminated mycobacterium avium complex infection", Eur J Clin Microbiol Infect Dis, 20, pp.199~201 (2001)
- Berger P, "Mycobacterium avium brain abscess at the initiation of highly active antiretroviral therapy", Eur J Clin Microbiol Infect Dis, 23, pp.142~144 (2004)
- Fortin C, "Cerebral Mycobacterium avium abscesses: Late immune reconstitution syndrome in an HIV-1- infected patient receiving highly active antiretroviral therapy", Can J Infect Dis Med Microbiol, 16, pp.187~189 (2005)
- Anonymous, "Diagnosis and treatment of disease caused by nontuberculous mycobacteria. This official statement of the American Thoracic Society was approved by the Board of Directors, March 1997. Medical Section of the American Lung Association", Am J Respir Crit Care Med, 156, pp.S1~S25 (1997)
- Gray F, "Neuropathologic study of 135 adult cases of acquired immunodeficiency syndrome (AIDS)", Ann Pathol, 11, pp.236~247 (1991)
- Gray F, "Pathology of the central nervous system in 40 cases of acquired immune deficiency syndrome (AIDS)", Neuropathol Appl Neurobiol, 14, pp.365~380 (1988)
- Cegielski JP, "Central nervous system infections with nontuberculous mycobacteria", Clin Infect Dis, 25, pp.1496~1497 (1997)
- Mathisen GE, "Brain abscess", Clin Infect Dis, 25, pp.763~781 (1997)
- Cárdenas G, "Tuberculous brain abscesses in immunocompetent patients: management and outcome", Neurosurgery, 67, pp.1081~1087 (2010)
- Katti MK, "Pathogenesis, diagnosis, treatment, and outcome aspects of cerebral tuberculosis", Med Sci Monit, 10, pp.RA215~RA229 (2004)
- Griffith DE, "An official ATS", IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases, 2007, pp.175, 367~416
- Benson CA, "A prospective, randomized trial examining the efficacy and safety of clarithromycin in combination with ethambutol, rifabutin, or both for the treatment of disseminated Mycobacterium avium complex disease in persons with acquired immunodeficiency syndrome", Clin Infect Dis, 37, pp.1234~1243 (2003)
- Dubé MP, "A randomized evaluation of ethambutol for prevention of relapse and drug resistance during treatment of Mycobacterium avium complex bacteremia with clarithromycin-based combination therapy. California Collaborative Treatment Group", J Infect Dis, 176, pp.1225~1232 (1997)
- Nau R, "Penetration of drugs through the blood-cerebrospinal fluid", blood-brain barrier for treatment of central nervous system infections, 2010, pp.23, 858~883
- Prasad KN, "Analysis of microbial etiology and mortality in patients with brain abscess", J Infect, 53, pp.221~227 (2006)
- Gupta RK, "Differentiation of tuberculous from pyogenic brain abscesses with in vivo proton MR spectroscopy and magnetization transfer MR imaging", AJNR Am J Neuroradiol, 22, pp.1503~1509 (2001)
- Chakraborti S, "Clinicopathological study of tuberculous brain abscess", Pathol Res Pract, 205, pp.815~822 (2009)
- Lu CH, "Bacterial brain abscess: microbiological features, epidemiological trends and therapeutic outcomes", QJM, 95, pp.501~509 (2002)