말초혈액도말에서 우연히 발견된 Pichia anomala 1예
A Case of Pichia anomala Detected Incidentally in Peripheral Blood Smear
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초록
면역저하 환자의 생존기간이 길어지면서 진균감염을 비롯한 병원성 기회감염이 증가하고 있다. 파종성 칸디다증이 가장 흔한 병원성 진균감염으로 알려져 왔으며 원인균으로 Candida albicans 외에 비-C. albicans 균종의 분리 빈도가 증가하고 있다. 저자들은 총 비경구영양법, 도관삽입 등의 치료를 받고 그에 따르는 장기간의 입원기간 동안 항생제 투여 등의 병력을 가진 환자의 말초혈액도말에서 우연히 다수의 효모균을 발견하고 혈액 배양과 흉막삼출액 배양으로 P. anomala를 분리동정하였기에 문헌고찰과 함께 보고하는 바이다.
Abstract
Nosocomial opportunistic infections including fungal infections continue to increase with a longer survival of immunocompromised patients. Disseminated candidiasis is the most common nosocomial fungal infection and the frequency of isolation of non-Candida albicans organisms besides C. albicans is increasing as causative organisms. We detected numerous yeast cells incidentally in a peripheral blood smear of an infant with congenital heart disease who was treated with total parenteral nutrition and catheterization, and had a history of antibiotics use during a long hospitalization period. Pichia anomala was isolated from the blood and pleural effusion.
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