서울지역 유통 식육 중의 세팔로스포린계 항균물질 잔류실태 조사
Monitoring for cephalosporins residues in raw meat in Seoul
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We investigated the residues of 6 cephalosporins (cefquinome, cephalexin, cephalonium, cefazolin, cef-tiofur, cefuroxime) using LC-MS/MS in raw meat in Seoul. This method involves extraction of the resi-due from the meat by distilled water and methanol followed by a manual of residue analysis published by the National Institute of Food and Drug Safety Evaluation. The recoveries ranged between 74.71∼90.01% in beef, 73.37∼101.40% in pork and 70.87∼95.53% in chicken, respectively. The limits of detection were 0.0004∼0.0563 mg/kg, and the limits of quantification were 0.001∼0.169 mg/kg respectively. Residues of cephalosporins which exceeded maximum residue limits (MRL) were not ex-ceed in any of the 287 samples. However, it is necessary to develop multi-method, which includes the active metabolites of ceftiofur.
Abstract
We investigated the residues of 6 cephalosporins (cefquinome, cephalexin, cephalonium, cefazolin, cef-tiofur, cefuroxime) using LC-MS/MS in raw meat in Seoul. This method involves extraction of the resi-due from the meat by distilled water and methanol followed by a manual of residue analysis published by the National Institute of Food and Drug Safety Evaluation. The recoveries ranged between 74.71∼90.01% in beef, 73.37∼101.40% in pork and 70.87∼95.53% in chicken, respectively. The limits of detection were 0.0004∼0.0563 mg/kg, and the limits of quantification were 0.001∼0.169 mg/kg respectively. Residues of cephalosporins which exceeded maximum residue limits (MRL) were not ex-ceed in any of the 287 samples. However, it is necessary to develop multi-method, which includes the active metabolites of ceftiofur.
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