마보플록삭신 제품별 접종이 비육돈 목심 부위 이상육 발생에 미치는 효과
Effects of marbofloxacin injection for granuloma formation in fattening pigs
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The abnormal meat could caused by abscess, fibrosis and granuloma in the region of the neck by ad-verse effect of vaccination or antibiotic injection under swine practice. In this study, the incidence of abnormal meat due to antibiotics injection was investigated using marbofloxacin from different man-ufacturers. To evaluate the incidence of abnormal meat via antibiotic treatment, a total of 440 pigs with the age of 140~150 days old were selected. Two hundred of pigs were assigned as a control group and 2 mL of saline was inoculated daily for three days. Two hundred forty of pigs were used as treat-ment group and further divided into 6 groups, consisting of 16% of original marbofloxacin treated, 10% of original marbofloxacin treated and 4 different kinds of generic marbofloxacin treated groups respectively. When test animals were slaughtered, incidence, type and size of induced abnormal meat were recorded. In the result of this study, statistical analysis found significantly lower incidence of abnormal meat formation was in 16% original marbofloxacin treated groups compared to the other tested groups (P <0.05). In the summary, antibiotic treatment could produce abnormal meat forma-tion but the 16% of original marbofloxacin had the most minimal abnormal meat formation effect.
Abstract
The abnormal meat could caused by abscess, fibrosis and granuloma in the region of the neck by ad-verse effect of vaccination or antibiotic injection under swine practice. In this study, the incidence of abnormal meat due to antibiotics injection was investigated using marbofloxacin from different man-ufacturers. To evaluate the incidence of abnormal meat via antibiotic treatment, a total of 440 pigs with the age of 140~150 days old were selected. Two hundred of pigs were assigned as a control group and 2 mL of saline was inoculated daily for three days. Two hundred forty of pigs were used as treat-ment group and further divided into 6 groups, consisting of 16% of original marbofloxacin treated, 10% of original marbofloxacin treated and 4 different kinds of generic marbofloxacin treated groups respectively. When test animals were slaughtered, incidence, type and size of induced abnormal meat were recorded. In the result of this study, statistical analysis found significantly lower incidence of abnormal meat formation was in 16% original marbofloxacin treated groups compared to the other tested groups (P <0.05). In the summary, antibiotic treatment could produce abnormal meat forma-tion but the 16% of original marbofloxacin had the most minimal abnormal meat formation effect.
참고문헌 (19)
- Anna R, "Adjuvants in veterinary vaccines : Modes of action and adverse effects", J Vet Intern Med, 17, pp.273~281 (2003)
- Applbaum PC, "The fluoroquinolone antibacterials : past, present and future perspective", Int J Antimicrob Agents, 16, pp.5~15 (2000)
- Bryce M, "Incidence and severity of Arcanobacterium pyogenes injection site abscesses with needle or needle-free injection", Meat Science, 92, pp.805~807 (2012)
- 최성현, "Economic burden of foot-and-mouth disease vaccination-induced injection site lesions in slaughtered pigs and its causal relationship", 예방수의학회지, 39(4), pp.153~156 (2015), 한국예방수의학회[DOI]
- Christensen G, "Disease of the respiratory system", Disease of Swine, pp.913~940 (1999)
- Dubeski P, "Tenderness of beef round muscles containing injection site lesions or bruises", Can J Anim Sci, 81, pp.441~449 (2001)
- Dudley MN, "Pharmacodynamics and pharmacokinetics of antibiotics with special references to the fluoroquinolones", Am J Med, 30, pp.45~50 (1991)
- 고은영, "Effects of Foot-and-mouth Disease Vaccination Location and Injection Device on the Incidence of Site Lesions in Pork", 한국축산식품학회지, 38(3), pp.498~505 (2018), 한국축산식품학회
- George M, "Injection-site lesions in carcasses of cattle receiving injections at branding and at weaning", J Anim Sci, 73, pp.3235~3240 (1995)
- Harper A, "Livestock update" (2008), Virginia Cooperative Extension
- Kahn C, "The Merk Veterinary Manual", pp.935~953 (2005), Merck Sharp & Dohme Corp
- Lefebre H, "Non-invasive and quantitative evaluation of post-injection muscle damage by pharmacokinetic analysis of creatine kinase release", Vet Res, 27, pp.343~361 (1996)
- Nouws JFM, "Irritation, bioavailability, and residue aspects of ten oxytetracycline formulations adiministered intramuscularly to pigs", Vet Quart, 6, pp.80~84 (1984)
- Nouws, Smulders, Rappalini, "A comparative study on irritation and residue aspects of five oxytetracycline formulations administered intramuscularly to calves, pigs and sheep", Vet Quart, 12, pp.129~138 (1990)
- Otake S, "Transmission of porcine reproductive and respiratory syndrome virus by needles", Vet Rec, 150, pp.114~115 (2002)
- Thomas E, "A field comparison of the efficacy and tolerance of marbofloxacin in the treatment of bovine respiratory disease", J Vet Pharmacol, 24, pp.353~358 (2001)
- Trinh H, "Susceptibility of Arcanobacterium pyogenes from different sources to tetracycline, macrolide and lincosamide antimicrobial agent", Vet Microbiol, 85, pp.353~359 (2002)
- Valtulini S, "Aluminium hydroxide-induced granulomas in pigs", Vaccine, 23, pp.3999~4004 (2005)
- 박유리, "시판 백신접종 스트레스 완화제의 돼지 구제역 백신 접종부위 부작용 발생 저감 효과 평가", 한국동물위생학회지, 40(3), pp.177~185 (2017), 한국동물위생학회
