본문 바로가기
KERD
논문KCI 등재

돼지유행성설사병(PEDV) 생독 ․ 사독백신의 면역형성 비교연구

A comparative study of imumno formation on the porcine epidemic diarrhea virus lives vaccine and inactivated vaccine

이지영|이은미|임정철|서형석|조현웅|허부홍|권미순
한국동물위생학회 (THE KOREAN SOCIETY OF VETERINARY SERVICE)|2009.09|한국동물위생학회지|제32권 제3호|pp. 201-207

2

조회

0

다운로드

0

인용

0

참고문헌

주제분류수의학

초록

Abstract

Three kind of porcine viruses, porcine transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV) and rotavirus are considered as the most important causative of diarrhea in piglets. The study established vaccination programs to prevent PEDV was applied to sow which inoculated twice vaccinations on 2-weeks-interval during the late term of pregnant sows with PEDV live vaccine A (LL) group, the B (LKK) group vaccination program was applied that one time single PEDV live vaccine at the pre-mate followed by the TGEV, PEDV combined inactivated vaccine (twice vaccination on 2-weeks interval at the third-trimester), and was applied to sow which inoculated twice vaccination on 2-weeksinterval during the late term of pregnant sows with by the TGEV, PEDV combined inactivated vaccine C (KK) group. By comparison with the serum neutralizing antibody titers against PEDV of the vaccination programs. As the result of SN test on sows in the pig farm before vaccination, was showed antibody titers of 9/45 (20.0%). A group and B group vaccination method was higher than those of C group in sows, and A group was sustained 8~64 in the breeding sows. In the piglets up to 2 weeks of age, A group was showed antibody titers of 17/22 (81.8%) that showed 2-128, and B group was showed antibody titers of 30/37 (81.1%) that showed 2-512, and C group was showed antibody titers of 14/28 (50.0%) that showed 2-32. Sows sera collected for Aujeszky’s disease survey from november 2005 to august 2006 were tested for the survey on PEDV antibody titers. As the results of SN test in 54 pig farms, antibody titers of 47/286 (16.4%) showed above 2. Five breeding farms were antibody titers of 38/77 (49.4%), Wanggung zone farms antibody titers of 59/85 (69.4%). In pigs farms, LLKK (256-1024 titer) PEDV vaccination program method was higher than those of LLLL (32 titer) in sows.

참고문헌 (17)

  1. 강영배, "돼지유행성설사 (Porcine epidemic diarrhea) 발생 피해, 병리진단 및 방역대책", 대한수의사회지, 31, pp.38~56 (1995)
  2. 권창희, "돼지 유행성 설사바이러스(porcine epidemic diarrhea virus)의 국내분리주 작성에 관한 연구", 대한수의학회지, 33(2), pp.249~254 (1993)
  3. 박남용, "돼지유행성 설사바이러스의 분리동정", 대한수의사회지, 29(6), pp.360~365 (1993)
  4. 박남용, "In situ hybridization에 의한 돼지유행성설사증의 국내발생 역추적 진단", 대한수의학회지, 37(4), pp.809~816 (1997)
  5. 지영철, "항혈청 투여에 따른 유행성 설사병 예방효과 I. 혈청학적검사, RT-PCR검사, 형광항체검사", 한국수의병리학회지, 6(1), pp.19~26 (2002)
  6. 돼지전염성위장염, 유행성설사, 로타바이러스감염증 3종혼합생백신 개발. 수의과학기술개발연구사업 연구과제최종보고서, "탁동섭", 건양기획, 681~703 (2004)
  7. Bohl, "Passive Immunity in transmissible gastroenteritis of swine : Intramuscula injection of pregnant swine with a modified live-virus vaccine", Am J Vet Res, 36(3), pp.267~271 (1975)
  8. Bohl EH, "The use of cell culture for study of swine", Proc US Livest Sanit Assoc, 69, pp.343~350 (1965)
  9. Duarte M, "Sequence analysis of the porcine epidemic diarrhea virus genome between the nucleocapsid and spike protein genes reveals polymorphic OFR", Virology, 198(2), pp.466~476 (1994)
  10. Egberink H, "Characterization of the structural protein of porcine epidemic diarrhea virus. strain CV777", Am J Vet Res, 49(8), pp.1320~1324 (1988)
  11. Hofmann M, "Propagation of the virus of porcine epidemic diarrhea in cell culture", J Cli Microbiol, 26(11), pp.2235~2239 (1988)
  12. Kim O, "Detection an differentiation of porcine epidemic diarrhea virus and transmissible gastroenteritis virus in clinical samples by multiplex RT-PCR", Vet Rec, 146(22), pp.637~640 (2000)
  13. Kusanagi K, "Isolation and serial propagation of porcine epidemic diarrhea virus in cell cultures and partial characterization of the isolation", J Vet Med Sci, 54(2), pp.313~318 (1992)
  14. Lanza I, "Lactogenic immunity and milk antibody serotypes to transmissible gastroenteritis virus in sows exposed to porcine respiratory coronavirus during pregnancy", Am J Vet Res, 56(6), pp.739~748 (1995)
  15. Saif LJ, "Coronavirus immunogens", Vet Microbiol, 37(3), pp.285~297 (1993)
  16. Shokley LJ, "Diagnosis of porcine and bovine enteric coronavirus infection using cloned cDNA probes", J Clin Microbiol, 25(9), pp.1592~1596 (1987)
  17. Straw BE, "Porcine epidemic diarrhea. Disease of swine 9 eds", pp.367~372 (2006), Iowa State Univ Press

관련 논문AI추천

포유자돈에서 돼지써코바이러스 2형이 돼지유행성설사 바이러스 감염에 미치는 영향 Ⅰ. 혈청학적 결과, 형광항체검사 및 RT-PCR 검사김문, 김영훈, 한정희한국동물위생학회 · 한국동물위생학회지2009 · 제32권 제3호한국 이유자돈에서 검출된 돼지 유행성 설사 바이러스의 유전자 서열 분석김영훈, 서태원, 신현근, 한정희한국동물위생학회 · 한국동물위생학회지2009 · 제32권 제1호IgY 투여에 따른 포유자돈의 설사에 대한 예방효과Ⅰ. 혈청학적 결과, 형광항체검사 및 RT-PCR 검사김문, 윤병일, 한정희한국동물위생학회 · 한국동물위생학회지2008 · 제31권 제1호포유자돈에서 돼지써코바이러스 2형이 돼지유행성설사 바이러스 감염에 미치는 영향 Ⅱ. 임상증상, 병리조직학적 검사 및 면역조직학적 검사김문, 김영훈, 한정희한국동물위생학회 · 한국동물위생학회지2009 · 제32권 제3호Evaluation of virulence reversion of an attenuated porcine epidemic diarrhea vaccine strain by serial passages in suckling pigletsDa-Jeong Kim, Gyeong-Seo Park, Hwan-Ju Kim, Sang Chul Kang, Seung-Chai Kim, Won-Il Kim한국동물위생학회 · 한국동물위생학회지2023 · 제46권 제3호돼지에서 구제역 백신 접종 후 항체가 변화 조사정광, 강순근, 권혁무, 배진규, 안길호, 왕영일, 정준용한국동물위생학회 · 한국동물위생학회지2013 · 제36권 제1호

이 간행물의 다른 논문 (13건)

포유자돈에서 돼지써코바이러스 2형이 돼지유행성설사 바이러스 감염에 미치는 영향 Ⅰ. 혈청학적 결과, 형광항체검사 및 RT-PCR 검사김영훈, 한정희, 김문pp. 177-187포유자돈에서 돼지써코바이러스 2형이 돼지유행성설사 바이러스 감염에 미치는 영향 Ⅱ. 임상증상, 병리조직학적 검사 및 면역조직학적 검사김영훈, 한정희, 김문pp. 189-200충남 서산태안지역에서 사육중인 송아지의 코로나바이러스 감염률 조사남이현, 이미성, 강형주, 전동민, 이재봉, 육심용, 한우수pp. 209-214Brittany Spaniel에서 Proteus mirabilis에 의한 유방염 발생: 증례고원석, 곽길한, 추금숙, 송희종, 이정원pp. 215-218Seroprevalence of specific Brucella infection of cattle in Bangladesh Agricultural University Veterinary Clinics and its surrounding areasMd Siddiqur Rahman, Nur Alam, A K M Anisur Rahman, Md Shamim Ahasan, 송희종pp. 219-225
원문 보기