사상자 추출물의 자돈 병원성 대장균 억제 효과
The effects of Torilis fructus extracts against enteropathogenic Escherichia coli in Piglets
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The antibiotic chemotherapy produces sometimes side effects and fails to eliminate bacterial infection. The occurrence of strains resistant to antibiotics would be expected to increase, and it is nowadays im-portant to search for non-antibiotic substances. We are aimed to evaluate the effects of Torilis fructus extracts against enteropathogenic Escherichia coli (E. coli) in Piglets. The piglets were divided with three groups; Negative control group, E. coli-infected positive control group, and the Torilis fructus ex-tracts treated group with E. coli infection. During the study period, we compared clinical signs, weight increase rate, fecal scores, gross findings between the treated group and non treated group. After nec-ropsy, necropsy findings and histopathological findings were conducted with the comparison between the groups. As the results of this study, the Torilis fructus extracts additive showed the effects on the suppression of E. coli-induced lesions. On the basis of this study results, our data suggest that the Torilis fructus extracts additive have the antimicrobial effects. The Torilis fructus extracts additive could be used as the alternative material for antimicrobial feed additives.
Abstract
The antibiotic chemotherapy produces sometimes side effects and fails to eliminate bacterial infection. The occurrence of strains resistant to antibiotics would be expected to increase, and it is nowadays im-portant to search for non-antibiotic substances. We are aimed to evaluate the effects of Torilis fructus extracts against enteropathogenic Escherichia coli (E. coli) in Piglets. The piglets were divided with three groups; Negative control group, E. coli-infected positive control group, and the Torilis fructus ex-tracts treated group with E. coli infection. During the study period, we compared clinical signs, weight increase rate, fecal scores, gross findings between the treated group and non treated group. After nec-ropsy, necropsy findings and histopathological findings were conducted with the comparison between the groups. As the results of this study, the Torilis fructus extracts additive showed the effects on the suppression of E. coli-induced lesions. On the basis of this study results, our data suggest that the Torilis fructus extracts additive have the antimicrobial effects. The Torilis fructus extracts additive could be used as the alternative material for antimicrobial feed additives.
참고문헌 (15)
- Anadon A, "Residues of antimicrobial drug and feed additives in animal products. Regulatory aspects", Livest Prod Sci, 59, pp.183~198 (1999)
- Blendinger K, "Hormaonal state and effects of the use of an antiprogestin in bitches with pyometra", J Reprod Fertil Suppl, 51, pp.317~325 (1997)
- Bonneau M, "Biotechnology in animal nutrition, physiology and health", Livest Prod Sci, 59, pp.223~241 (1999)
- Buenz EJ, "A randomized Phase I study of Atuna racemosa: a potential new anti-MRSA natural product extract", J Ethnopharmacol, 114, pp.371~376 (2007)
- Cromwell GL, "Antimicrobial and promicrobial agents, In Swine Nutrition. 2nd ed", pp.401~ (2001), CRC Press
- Deen J, "Health and production managemaent in swine herds, In Herd Health: Food animal Production Medicine 3th ed", pp.635~764 (2001), Saunders Co., W.B.
- Koehn FE, "The evolving role of natural products in drug discovery", Nat Rev Drug Discov, 4, pp.206~220 (2005)
- Kunin CM, "Resistance to antimicrobial drugs-a worldwide calcmity", Ann Intern Med, 118, pp.557~561 (1993)
- 이금홍, "補血 藥材인 당귀, 지황, 백작약, 하수오의 면역 촉진 효과 비교 분석", 동의생리병리학회지, 20(6), pp.1507~1515 (2006), 대한동의병리학회
- Lee HA, "Antiviral Effect of Natural Herb Extract WK01 and WK02 against Porcine Epidemic Diarrhea Virus", J Life Sci Nat Res, 30, pp.61~71 (2008)
- Lim TH, "Antifungal activity and identification of an Actinomycetes straun isolated from mummified peaches", Korean J Appl Microbiol Biotechnol, 28, pp.161~166 (2002)
- Liu CS, "Antibacterial properties of Chinese herbal medicines against nosocomial antibiotic resistant strains of Pseudomonas aeruginosa in Taiwan", Am J Chin Med, 35, pp.1047~1060 (2007)
- 서승용, "흑대두․감초 혼합추출물이 생쥐의 비장세포 및 대식세포의 활성에 미치는 영향", 동의생리병리학회지, 23(6), pp.1385~1391 (2009), 대한동의병리학회
- 심재근, "야채스프의 RAW 264.7 세포에서 항염증 효과", 한국식품영양과학회지, 39(8), pp.1097~1101 (2010), 한국식품영양과학회
- Van LI, "Emergence of Methicillin- Resistant Staphylococcus aureus of Animal Origin in Humans", Emerg Infect Dis, 13, pp.1834~1839 (2007)