추출 공정 다변화를 통한 홍경천의 항암활성 증진효과

Abstract

This study was performed to compare effect of anticancer activities on Rhodiola sachalinensis by ultrasonification process and solvent. Compared the yield to the water extracts (WE), water extracts with ultrasonification (WEU) at 60, 100℃ and ethyl alcohol extracts (EE), ethyl alcohol extracts with ultrasonification (EEU) at 60℃ from Rhodiola sachalinensis. Experimental studies were progressed through the anticancer activities such as cell cytotoxicity, inhibition activities of cell growth. The cell cytotoxicity using human embryonic kidney cell (HEK293) was showed cytotoxicity of below 26.26% by extracts of Rhodiola sachalinensis in 1.0 ㎎/㎖ concentration. The anticancer activities were increased in over 70% by extracts of Rhodiola sachalinensis in A549, AGS, Hep3B and MCF-7 cells. From the results, the extract of Rhodiola sachalinensis were showed useful anticancer activities.