짚신나물, 삼백초의 항산화와 항암활성 효과
Antioxidant and Anticancer Effects of Agrimony (Agrimonia pilosa L.) and Chinese Lizardtail (Saururus chinensis Baill)
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The antioxidant activities of Agrimony (Agrimonia pilosa L.) and Chinese lizardtail (Saururus chinensis Baill)according to extraction methods were measured. SOD-like activity showed greater antioxidant effects with ethanol solventthan those with water. Ethanol extracts of Agrimony leaves showed the highest SOD-like activity of 94.4%. SOD-like activitydiffered according to the extraction solvents. The contents of polyphenolic compounds were higher in water extracts thanthose in ethanol extracts. The contents were 161.4. for Agrimony roots, 100.2. for Agrimony leaves, and 79.1. forAgrimony stalks in order. EDA in Agrimony leaves that were highest among medicinal plants were 83.4% in the waterextract and 81.7% in the ethanol extract. The anticancer effects of the extracts by water and ethanol from Agrimony andfractions of Agrimony and also the growth of liver cancer cells, Hep3B was inhibited 83.2% by the hexane fractions of Agri-mony, while the growth of normal cell, DC2.4 was not affected.
Abstract
The antioxidant activities of Agrimony (Agrimonia pilosa L.) and Chinese lizardtail (Saururus chinensis Baill)according to extraction methods were measured. SOD-like activity showed greater antioxidant effects with ethanol solventthan those with water. Ethanol extracts of Agrimony leaves showed the highest SOD-like activity of 94.4%. SOD-like activitydiffered according to the extraction solvents. The contents of polyphenolic compounds were higher in water extracts thanthose in ethanol extracts. The contents were 161.4. for Agrimony roots, 100.2. for Agrimony leaves, and 79.1. forAgrimony stalks in order. EDA in Agrimony leaves that were highest among medicinal plants were 83.4% in the waterextract and 81.7% in the ethanol extract. The anticancer effects of the extracts by water and ethanol from Agrimony andfractions of Agrimony and also the growth of liver cancer cells, Hep3B was inhibited 83.2% by the hexane fractions of Agri-mony, while the growth of normal cell, DC2.4 was not affected.
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