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안정기 양극성 장애환자의 얼굴자극에 대한 주의력 유지과제에서의 결핍 특성

Attention Deficits of Euthymic Bipolar Patients in the Sustained Attention to Response Task

석정호|전덕인|박진영|전재영|조현상|김세주|황성식
대한신경정신의학회 (Korean Neuropsychiatric Association)|2007.05|신경정신의학 (JOURNAL OF THE KOREAN NEUROPSYCHIATRIC ASSOCIATION)|제46권 제3호|pp. 229-236

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참고문헌

키워드

양극성 장애·주의력 결핍·안정기.Bipolar disorder· Atention deficit· Euthymic phase.
주제분류정신과학

초록

이번 연구는 안정기 상태의 양극성 장애 환자에 있어 정상 대조군에 비해 주의력 유지기능의 결핍이 있었다는 것을 재확인하였고 숫자자극에 비해 얼굴자극에 대해 주의력 유지기능의 결핍이 두드러지다는 것을 관찰하였다. 이러한 결핍은 안정기 양극성 장애 환자의 사회직업적 기능에 제한을 가져오는 요인이 될 수 있으며 이에 대한 치료적 개입의 필요성을 시사한다. 앞으로 안정기의 우울증 환자 혹은 다른 정신질환을 갖고있는 환자들과 조증기의 양극성 장애 환자들을 포함한 다양한 임상적 환자군과의 비교 연구를 통해 안정기 양극성 장애 환자의 주의력 유지기능 결핍 양상을 구체적으로 밝혀나갈 필요가 있을 것으로 생각한다. 아울러 다양한 자극과 정서조건을 보완한 추가적인 연구를 통해 이러한 결핍양상을 보다 구체적으로 밝혀가는 연구가 이루어져야 할 것으로 생각한다.

Abstract

Objectives: Euthymic patients with bipolar disorder have been reported to show deficit in sustained attention. This study aimed to compare the attention capacities of euthymic bipolar patients with those of control subjects using the sustained attention to response task (SART) and to examine the differences in the performance of SART related to the stimulus type. Methods: The four SART tasks were performed to measure attention capacities in 42 euthymic patients with bipolar disorder and 28 control subjects. Happy, neutral, fearful faces and digit ‘3’ were used as target stimuli in happy, neutral, fear and digit task conditions, respectively. The severity of mood symptom was assessed with 17-item Hamilton Rating Scale for Depressive symptoms and Young Mania Rating Scale for manic symptoms. The efficiency estimate which reflects both the response accuracy and speed was used as the main outcome variable. Results: Bipolar patients showed significantly lower correct response rate than control group in all task conditions. Efficiency estimates of the bipolar patient group were significantly lower than those of the control group in the SART using facial stimuli but not in the digit task condition. There was no significant difference in task performance related to the emotional categories of facial stimuli. Conclusion: Bipolar patients showed deficit in sustained attention even in the euthymic state. The attention deficits shown in the euthymic bipolar patients may be prominent in a more complex task condition such as facial stimuli.

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