본문 바로가기
KERD
논문KCI 등재

뇌졸중후우울증의 발병기전 : 생물-심리-사회적 통합 모형

Pathogenesis of Post-Stroke Depression : A Bio-Psycho-Social Integrative Model

2

조회

0

다운로드

4

인용

0

참고문헌

키워드

주제분류정신과학

초록

Depression is common after a stroke and has adverse effects on both the course and prognosis. A proper understanding on the pathogenetic mechanisms of post-stroke depression (PSD) is the first step in the treatment of PSD. PSD should not be considered a purely organic neurological mood syndrome but rather the consequence of a complex interaction model of biological, psychological, and social factors. Based on the pathogenesis, a bio-psycho-social approach is mandatory in the treatment of PSD. A medical team with an integrative bio-psycho-social view should take a pivotal role in the management of PSD.

Abstract

Depression is common after a stroke and has adverse effects on both the course and prognosis. A proper understanding on the pathogenetic mechanisms of post-stroke depression (PSD) is the first step in the treatment of PSD. PSD should not be considered a purely organic neurological mood syndrome but rather the consequence of a complex interaction model of biological, psychological, and social factors. Based on the pathogenesis, a bio-psycho-social approach is mandatory in the treatment of PSD. A medical team with an integrative bio-psycho-social view should take a pivotal role in the management of PSD.

참고문헌 (76)

  1. Roger VL, "Heart disease and stroke statistics--2011 update: a report from the American Heart Association", Circulation, 123, pp.18~209 (2011)
  2. "Death statistics"[URL]
  3. Olsen TS, "Arm and leg paresis as outcome predictors in stroke rehabilitation", Stroke, 21, pp.247~251 (1990)
  4. Starkstein SE, "Neuropsychiatric aspects of stroke. In Textbook of Geriatric Psychiatry", pp.457~475 (1994), Washington DC: American Psychiatric Press
  5. Angelelli P, "Development of neuropsychiatric symptoms in poststroke patients: a cross-sectional study", Acta Psychiatr Scand, 110, pp.55~63 (2004)
  6. Hackett ML, "Frequency of depression after stroke: a systematic review of observational studies", Stroke, 36, pp.1330~1340 (2005)
  7. 강희주, "뇌졸중후우울증의 유병율 및 예측인자", 우울조울병, 9(2), pp.57~63 (2011), 대한우울•조울병학회
  8. Kim JM, "Associations of cytokine gene polymorphisms with post-stroke depression", World J Biol Psychiatry (2011)
  9. Pohjasvaara T, "Depression is an independent predictor of poor long-term functional outcome post-stroke", Eur J Neurol, 8, pp.315~319 (2001)
  10. Herrmann N, "The Sunnybrook Stroke Study: a prospective study of depressive symptoms and functional outcome", Stroke, 29, pp.618~624 (1998)
  11. Spalletta G, "Predictors of cognitive level and depression severity are different in patients with left and right hemispheric stroke within the first year of illness", J Neurol, 249, pp.1541~1551 (2002)
  12. Gillen R, "Depressive symptoms and history of depression predict rehabilitation efficiency in stroke patients", Arch Phys Med Rehabil, 82, pp.1645~1649 (2001)
  13. Morris PL, "Association of depression with 10-year poststroke mortality", Am J Psychiatry, 150, pp.124~129 (1993)
  14. Williams LS, "Depression and other mental health diagnoses increase mortality risk after ischemic stroke", Am J Psychiatry, 161, pp.1090~1095 (2004)
  15. Hackett ML, "Interventions for Treating Depression After Stroke", Stroke (2009)
  16. Watkins CL, "otivational interviewing early after acute stroke: a randomized, controlled trial", Stroke, 38, pp.1004~1009 (2007)
  17. Zhao HW, "Effect of mental intervention on post-stroke depression and rehabilitation of neurological function", Chinese J Clin Rehabil, 8, pp.2408~2409 (2004)
  18. Lincoln NB, "Cognitive behavioral psychotherapy for depression following stroke: a randomized controlled trial", Stroke, 34, pp.111~115 (2003)
  19. Towle D, "Evaluation of social work on depression after stroke", Clin Rehabil, 3, pp.89~96 (1989)
  20. Folstein MF, "Mood disorder as a specific complication of stroke", J Neurol Neurosurg Psychiatry, 40, pp.1018~1020 (1977)
  21. Starkstein SE, "Anosognosia and major depression in 2 patients with cerebrovascular lesions", Neurology, 40, pp.1380~1382 (1990)
  22. Fujikawa T, "Incidence of silent cerebral infarction in patients with major depression", Stroke, 24, pp.1631~1634 (1993)
  23. Robinson RG, "Pharmacological treatment following experimental cerebral infarction: implications for understanding psychological symptoms of human stroke", Biol Psychiatry, 12, pp.669~680 (1977)
  24. Dieguez S, "Is poststroke depression a vascular depression", Neurol Sci, 226, pp.53~58 (2004)
  25. Desmond DW, "Ischemic stroke and depression", J Int Neuropsychol Soc, 9, pp.429~439 (2003)
  26. Provinciali L, "Depression after first-ever ischemic stroke: the prognostic role of neuroanatomic subtypes in clinical practice", Cerebrovasc Dis, 26, pp.592~599 (2008)
  27. Lipsey JR, "Mood change following bilateral hemisphere brain injury", Br J Psychiatry, 143, pp.266~273 (1983)
  28. Parikh RM, "A two year longitudinal study of poststroke mood disorders: prognostic factors related to one and two year outcome", Int J Psychiatry Med, 18, pp.45~56 (1988)
  29. Aström M, "Major depression in stroke patients. A 3-year longitudinal study", Stroke, 24, pp.976~982 (1993)
  30. Morris PL, "Lesion location and poststroke depression", J Neuropsychiatry Clin Neurosci, 8, pp.399~403 (1996)
  31. Dam H, "Depression among patients with stroke", Acta Psychiatr Scand, 80, pp.118~124 (1989)
  32. MacHale SM, "Depression and its relation to lesion location after stroke", J Neurol Neurosurg Psychiatry, 64, pp.371~374 (1998)
  33. Collin SS, "Depression after stroke", Clin Rehabil, 1, pp.27~32 (1987)
  34. Sharpe M, "Mood disorders in long-term survivors of stroke: associations with brain lesion location and volume", Psychol Med, 20, pp.815~828 (1990)
  35. Pohjasvaara T, "Frequency and clinical determinants of poststroke depression", Stroke, 29, pp.2311~2317 (1998)
  36. Carson AJ, "Depression after stroke and lesion location: a systematic review", Lancet, 356, pp.122~126 (2000)
  37. Bhogal SK, "Lesion location and poststroke depression: systematic review of the methodological limitations in the literature", Stroke, 35, pp.794~802 (2004)
  38. Perini F, "Temporal profile of serum anti-inflammatory and pro-inflammatory interleukins in acute ischemic stroke patients", Neurol Sci, 22, pp.289~296 (2001)
  39. Vila N, "Levels of anti-inflammatory cytokines and neurological worsening in acute ischemic stroke", Stroke, 34, pp.671~675 (2003)
  40. Babcock TA, "Transcriptional activation of indoleamine dioxygenase by interleukin 1 and tumor necrosis factor alpha in interferon-treated epithelial cells", Cytokine, 12, pp.588~594 (2000)
  41. Dantzer R, "Cytokine-induced sickness behavior: mechanisms and implications", Ann N Y Acad Sci, 933, pp.222~234 (2001)
  42. Maes M, "Interleukin-1 beta: a putative mediator of HPA axis hyperactivity in major depression", Am J Psychiatry, 150, pp.1189~1193 (1993)
  43. Musselman DL, "Paroxetine for the prevention of depression induced by high-dose interferon alfa", N Engl J Med, 344, pp.961~966 (2001)
  44. Spalletta G, "The etiology of poststroke depression: a review of the literature and a new hypothesis involving inflammatory cytokines", Mol Psychiatry, 11, pp.984~991 (2006)
  45. Yang L, "The serum interleukin-18 is a potential marker for development of post-stroke depression", Neurol Res, 32, pp.340~346 (2010)
  46. Heils A, "Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene", J Neural Transm Gen Sect, 102, pp.247~254 (1995)
  47. Anguelova M, "A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders", Mol Psychiatry, 8, pp.574~591 (2003)
  48. Ramasubbu R, "Serotonin transporter gene promoter region polymorphism associated with poststroke major depression", J Neuropsychiatry Clin Neurosci, 18, pp.96~99 (2006)
  49. Kohen R, "Association of serotonin transporter gene polymorphisms with poststroke depression", Arch Gen Psychiatry, 65, pp.1296~1302 (2008)
  50. Lovejoy EA, "The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit", Eur J Neurosci, 17, pp.417~420 (2003)
  51. Battersby S, "Structure of a variable number tandem repeat of the serotonin transporter gene and association with affective disorder", Psychiatr Genet, 6, pp.177~181 (1996)
  52. Ramasubbu R, "Extended evaluation of serotonin transporter gene functional polymorphisms in subjects with post-stroke depression", Can J Psychiatry, 53, pp.197~201 (2008)
  53. Egan MF, "The BDNF val66met polymorphism affects activitydependent secretion of BDNF and human memory and hippocampal function", Cell, 112, pp.257~269 (2003)
  54. Kim JM, "BDNF genotype potentially modifying the association between incident stroke and depression", NEUROBIOLOGY OF AGING, 29(5), pp.789~792 (2008), ELSEVIER SCIENCE INC
  55. Fedoroff JP, "Are depressive symptoms nonspecific in patients with acute stroke", Am J Psychiatry, 148, pp.1172~1176 (1991)
  56. Paradiso S, "Vegetative and psychological symptoms associated with depressed mood over the first two years after stroke", Int J Psychiatry Med, 27, pp.137~157 (1997)
  57. Kendler KS, "The prediction of major depression in women: toward an integrated etiologic model", Am J Psychiatry, 150, pp.1139~1148 (1993)
  58. Sharpe M, "Depressive disorders in long-term survivors of stroke. Associations with demographic and social factors, functional status, and brain lesion volume", Br J Psychiatry, 164, pp.380~386 (1994)
  59. Lieberman D, "Characterization of elderly patients in rehabilitation: stroke versus hip fracture", Disabil Rehabil, 21, pp.542~547 (1999)
  60. Morris PL, "The relationship between risk factors for affective disorder and poststroke depression in hospitalised stroke patients", Aust N Z J Psychiatry, 26, pp.208~217 (1992)
  61. Andersen G, "Risk factors for post-stroke depression", Acta Psychiatr Scand, 92, pp.193~198 (1995)
  62. Ouimet MA, "Psychosocial risk factors in poststroke depression: a systematic review", Can J Psychiatry, 46, pp.819~828 (2001)
  63. Hackett ML, "Predictors of depression after stroke: a systematic review of observational studies", Stroke, 36, pp.2296~2301 (2005)
  64. Bogousslavsky J, "William Feinberg lecture 2002: emotions, mood, and behavior after stroke", Stroke, 34, pp.1046~1050 (2003)
  65. Berg A, "Depression and its assessment among stroke patients and their caregivers" (2009), Helsinki: Helsinki univ
  66. Allport GW, "Personality: A Psychological interpretation. 1st ed" (1937), London: Henry Holt and Company
  67. Ormel J, "The interplay and etiological continuity of neuroticism, difficulties, and life events in the etiology of major and subsyndromal, first and recurrent depressive episodes in later life", Am J Psychiatry, 158, pp.885~891 (2001)
  68. Morris PL, "Personality neuroticism and depression after stroke", Int J Psychiatry Med, 25, pp.93~102. (1995)
  69. Aben I, "Personality and vulnerability to depression in stroke patients: a 1-year prospective follow-up study", Stroke, 33, pp.2391~2395 (2002)
  70. Robinson RG, "The clinical neuropsychiatry of stroke. 2nd ed" (2006), Cambridge, MA: Cambridge University Press
  71. Verdelho A, "Depressive symptoms after stroke and relationship with dementia: A three-year follow-up study", Neurology, 62, pp.905~911 (2004)
  72. King RB, "Adaptation to stroke: a longitudinal study of depressive symptoms, physical health, and coping process", Top Stroke Rehabil, 9, pp.46~66 (2002)
  73. Eriksson M, "Self-reported depression and use of antidepressants after stroke: a national survey", Stroke, 35, pp.936~941 (2004)
  74. Chau JP, "Depression among Chinese stroke survivors six months after discharge from a rehabilitation hospital", J Clin Nurs, 19, pp.3042~3050 (2010)
  75. Berg A, "Poststroke depression in acute phase after stroke", Cerebrovasc Dis, 12, pp.14~20 (2001)
  76. Williams LS, "Care management of poststroke depression: a randomized, controlled trial", Stroke, 38, pp.998~1003 (2007)

관련 논문AI추천

이 간행물의 다른 논문 (9건)