정신분열병 환자와 직계 가족의 마음이론 능력 결함
Theory of Mind Deficits in Schizophrenia Patients and Their First-Degree Relatives
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초록
본 연구는 정신분열병 환자, 정신분열병 환자의 직계가족, 정상군을 대상으로 사회인지의 한 측면인 마음이론 과제 실시를 통하여 군 간의 차이를 규명하려 하였다. 연구결과 정신분열병 환자군과 정신분열병 환자의 직계가족군에서 정상인군과 비교하여 마음이론 능력의 결함을 관찰하였다. 정신분열병 환자의 직계가족군은 정상군과 비교하여 정신분열형 인격 척도 점수의 차이가 없었음에도 불구하고 마음이론 수행능력의 결함이 관찰되었다. 우리의 연구결과는‘마음 이론 결핍’ 현상을 정신분열병의 잠정적인 내적표현형으로 볼 수 있음을 시사한다.
Abstract
Objectives: Theory of mind (ToM) is the ability to conceptualize other people’s mental states in order to explain their behavior. This study compared the ToM ability of schizophrenia patients, their first-degree biological relatives, and healthy controls. Methods: ToM animation test was administered to schizophrenia patients (N=28), their healthy first-degree relatives (N=26), and healthy controls (N=28). The Korean version of schizotypal personality questionnaire (SPQ) was used to assess the schizotypal personality trait of all three groups. Results: Schizophrenia patients and their first-degree relatives showed decreased accuracy on ToM animation test compared to healthy controls [F(2,78)=29.75, p<.001]. Additionally, first-degree relatives performed worse than the control group and better than schizophrenia patients. First-degree relatives had similar SPQ scores compared to healthy controls but showed decreased ToM accuracy compared to healthy controls. Conclusion: ToM deficits in schizophrenia patients are apparent. The ToM deficit in first-degree relatives of schizophrenia patients raises the possibility that ToM deficit may be a endophenotype for schizophrenia pathology.
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