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신체 구성비와 인지기능과의 연관성 : 생체전기임피던스법을 이용한 연구

Relationship between Body Composition and Cognitive Function : Using Bioelectrical Impedance Analysis

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초록

Objective:Body composition is measured using bioelectrical impedance analysis (BIA), and correlation between the result of BIA and cognitive function is analyzed. Methods:A total of 118 elderly (46 male, 72 female) were recruited. They were divided into three groups; normal (n=33), mild cognitive impairment (n=42), and Alzheimer’s dementia (n=43) according to the diagnostic criteria. Skeletal muscle mass, body fat mass, and fat-free mass were measured using a BIA device, and were converted to the ratio of body weight. All participants underwent Korean version of Mini-Mental State Examination (MMSE-K). Results:In pearson correlation analysis, skeletal muscle percentage (SMP) and fat-free mass percentage (FFMP) were positively correlated with MMSE-K score (r=0.309, p=0.001; r=0.245, p=0.008), and body fat percentage was negatively correlated (r= -0.258, p=0.005). In multiple regression analysis, SMP (β=2.012, t=4.457, p<0.001) and FFMP (β=-1.733, t=-3.838, p<0.001) were selected as the best predictors of changes in MMSE-K score (R2=0.198). Conclusion:Reduced skeletal muscle and increased body fat correlate with decreased cognitive function, suggesting the need for prevention of frailty and early diagnosis of cognitive impairment.

Abstract

Objective:Body composition is measured using bioelectrical impedance analysis (BIA), and correlation between the result of BIA and cognitive function is analyzed. Methods:A total of 118 elderly (46 male, 72 female) were recruited. They were divided into three groups; normal (n=33), mild cognitive impairment (n=42), and Alzheimer’s dementia (n=43) according to the diagnostic criteria. Skeletal muscle mass, body fat mass, and fat-free mass were measured using a BIA device, and were converted to the ratio of body weight. All participants underwent Korean version of Mini-Mental State Examination (MMSE-K). Results:In pearson correlation analysis, skeletal muscle percentage (SMP) and fat-free mass percentage (FFMP) were positively correlated with MMSE-K score (r=0.309, p=0.001; r=0.245, p=0.008), and body fat percentage was negatively correlated (r= -0.258, p=0.005). In multiple regression analysis, SMP (β=2.012, t=4.457, p<0.001) and FFMP (β=-1.733, t=-3.838, p<0.001) were selected as the best predictors of changes in MMSE-K score (R2=0.198). Conclusion:Reduced skeletal muscle and increased body fat correlate with decreased cognitive function, suggesting the need for prevention of frailty and early diagnosis of cognitive impairment.

참고문헌 (37)

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