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한국 성인의 대사 위험인자 패턴 및 영양상태와 심뇌혈관질환 또는 지방간 발생 위험률: 전향적 코호트 연구

Cardiocerebrovascular Disease or Fatty Liver Incidence Associated with Pattern of Metabolic Risk Factors and Nutritional Status of Korean Adults: A Prospective Cohort Study

박미연|박필숙|이미성|딩총위
한국보건정보통계학회 (The Korean Society of Health informatics statistics)|2023.05|보건정보통계학회지 (Journal of Health Informatics and Statistics)|제48권 제2호|pp. 165-178|DOI 10.21032/jhis.2023.48.2.165

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참고문헌

키워드

IncidenceNutritional statusFatty liverPattern of metabolic risk factorsCardiocerebrovascular disease

초록

Objectives: To determine the nutrient intake according to patterns of metabolic risk factors, and examine the relationship between patterns of meta- bolic risk factors and incidence of cardiocerebrovascular disease or fatty liver in Korean adults. Methods: Data from the Korean Genome and Epidemiol- ogy Study were used to analyze 7,019 adults aged 50-64 years old. Depending on patterns of metabolic risk factors, participants were classified into four categories: ‘normal, NOR’, ‘obesity risk factors, ORF’ , ‘vascular risk factors, VRF’, ‘cluster risk factors, CRF’. Cox regression analysis was used to evaluate the incidence of cardiocerebrovascular disease or fatty liver. Results: The mean adequacy ratio (MAR) of VRF pattern women was significantly lower than that of the normal women. In Model 3, the incidence of cardiovascular disease or fatty liver decreased by 64.4% (hazard ratio (HR), 0.36; 95% confidence interval (CI), 0.15-0.84) in MAR Q3 women compared to MAR Q1 women. In Model 2 adjusted for age and energy intake, the incidence of cardiovascular disease or fatty liver increased by 87.6% (HR, 1.88; 95% CI, 1.01-3.48) in CRF pattern women compared to NOR women, but there was no significant dif- ference in Model 3. Conclusions: The study showed that among women, VRF patterns were associated with poor nutrient intake. There was an associa- tion between nutrient intake levels and metabolic risk factor patterns in women. Therefore, these findings can be used a basis to emphasize the need to establish nutrition management strategies tailored to individual’s metabolic risk status, for the prevention and management of metabolic syndrome complications.

Abstract

Objectives: To determine the nutrient intake according to patterns of metabolic risk factors, and examine the relationship between patterns of meta- bolic risk factors and incidence of cardiocerebrovascular disease or fatty liver in Korean adults. Methods: Data from the Korean Genome and Epidemiol- ogy Study were used to analyze 7,019 adults aged 50-64 years old. Depending on patterns of metabolic risk factors, participants were classified into four categories: ‘normal, NOR’, ‘obesity risk factors, ORF’ , ‘vascular risk factors, VRF’, ‘cluster risk factors, CRF’. Cox regression analysis was used to evaluate the incidence of cardiocerebrovascular disease or fatty liver. Results: The mean adequacy ratio (MAR) of VRF pattern women was significantly lower than that of the normal women. In Model 3, the incidence of cardiovascular disease or fatty liver decreased by 64.4% (hazard ratio (HR), 0.36; 95% confidence interval (CI), 0.15-0.84) in MAR Q3 women compared to MAR Q1 women. In Model 2 adjusted for age and energy intake, the incidence of cardiovascular disease or fatty liver increased by 87.6% (HR, 1.88; 95% CI, 1.01-3.48) in CRF pattern women compared to NOR women, but there was no significant dif- ference in Model 3. Conclusions: The study showed that among women, VRF patterns were associated with poor nutrient intake. There was an associa- tion between nutrient intake levels and metabolic risk factor patterns in women. Therefore, these findings can be used a basis to emphasize the need to establish nutrition management strategies tailored to individual’s metabolic risk status, for the prevention and management of metabolic syndrome complications.

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관련 논문AI추천

High-Carbohydrate Diets and Food Patterns and Their Associations with Metabolic Disease in the Korean Population송수진, 송윤주, 이윤정연세대학교의과대학 · Yonsei Medical Journal2018 · 제59권 제7호한국 성인의 식사의 규칙성에 따른 영양소 섭취와 심혈관계 위험인자박세아, 박현아대한임상건강증진학회 · Korean Journal of Health Promotion2010 · 제10권 제2호A healthy dietary pattern consisting of a variety of food choices is inversely associated with the development of metabolic syndrome신철, 백인경, 이명숙, 이재연, 전누리한국영양학회 · Nutrition Research and Practice2013 · 제7권 제3호Association between Dietary Carbohydrate Intake and Cardiovascular Risk Factors According to Low-Density Lipoprotein Cholesterol Levels in Korean Adults송수진, 송윤주, 이윤정대한임상건강증진학회 · Korean Journal of Health Promotion2020 · 제20권 제4호The framingham risk score, diet, and inflammatory markers in Korean men with metabolic syndrome김주영, 배우경, 손정민한국영양학회 · Nutrition Research and Practice2012 · 제6권 제3호Association between adherence to the Korean Food Guidance System and the risk of metabolic abnormalities in Koreans백현욱, 백희영, 송수진, 정현주, 정효지, 한성림한국영양학회 · Nutrition Research and Practice2011 · 제5권 제6호

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