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신경성 식욕부진을 보이는 젊은 무월경 여성에서의 골다공증

Osteoporosis in Amenorrheic Women with Anorexia Nervosa

정혜원|이지영
대한골다공증학회 (THE KOREAN SOCIETY OF OSTEOPOROSIS)|2009.04|OSTEOPOROSIS (The Journal of Korean Society of Osteoporosis)|제7권 제1호|pp. 6-14

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참고문헌

키워드

Anorexia NervosaOsteoporosisAmenorrhea
주제분류기타의약학

초록

Anorexia nervosa and other diet–related amenorrhea are associated with low bone mineral density in adults and adolescents. This is particularly important because these conditions usually arise in adolescent, when peak bone mass is maximally achieved. Possible contributors to low BMD in anorexia nervosa include hypoestrogenism, undernutrition with decreased lean body mass, hypercortisolemia, decreased IGF-I with GH resistance. Support for the use of hormone therapy alone to increase BMD in amenorrheic anorexic women is limited, and its routine use should be discouraged. The mainstay of treatment for improving BMD in anorexic women is increased caloric intake such that body mass is increased and there is a resumption of menses.

Abstract

Anorexia nervosa and other diet–related amenorrhea are associated with low bone mineral density in adults and adolescents. This is particularly important because these conditions usually arise in adolescent, when peak bone mass is maximally achieved. Possible contributors to low BMD in anorexia nervosa include hypoestrogenism, undernutrition with decreased lean body mass, hypercortisolemia, decreased IGF-I with GH resistance. Support for the use of hormone therapy alone to increase BMD in amenorrheic anorexic women is limited, and its routine use should be discouraged. The mainstay of treatment for improving BMD in anorexic women is increased caloric intake such that body mass is increased and there is a resumption of menses.

참고문헌 (47)

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