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광주 지역 여성의 연령에 따른 골밀도 변화

Bone Mineral Density by Age in Gwangju Women

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대한골다공증학회 (THE KOREAN SOCIETY OF OSTEOPOROSIS)|2010.08|OSTEOPOROSIS (The Journal of Korean Society of Osteoporosis)|제8권 제2호|pp. 203-210

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키워드

폐경골다공증Osteoporosis골밀도Bone mineral densityMenopause광주 여성Gwangju women
주제분류기타의약학

초록

목적: 다른 질환이 없는 광주 지역 여성의 골밀도를 조사하여 골다공증의 유병률을 평가하고자 하였다. 방법: 2007년 12월부터 2010년 4월까지 조선대학교 병원을 방문한 20세에서 88세 사이의 여성 1476명을 대상으로 요추와 대퇴골 부위에서 이중 에너지 엑스레이 흡착기를 사용하여 골밀도를 측정하고(GE-LUNA Progidy) 골다공증을 평가하였다. 결과: 1476명의 골다공증 유병률은 20대부터 연령대별로 요추에서 19명(12.8%), 19명(12.1%), 95명(18.8%), 158명(42.2%), 97명(74.0%), 115명(71.7%), 대퇴골 경부에서 0명(0%), 5명(3.4%), 11명(2.2%), 55명(14.7%), 65명(49.6%), 101명(63.3%), 대퇴골 전체에서는 0명(0%), 3명(1.7%), 3명(0.6%), 11명(2.9%), 22명(16.8%), 53명(33.3%)이었다. 결론: 현재 골밀도 검사에서 골다공증 기준은 폐경 후 여성을 기준으로 한 것이나, 폐경 전 여성에서 골밀도가 낮은 경우에 대해서도 기저 질환에 대한 검사가 필요하고 폐경 전 여성의 골밀도에 대한 기준이 정립되어야 한다고 사료된다.

Abstract

Objectives: The purpose of this study was to evaluate the prevalence of osteoporosis in Gwangju women. Methods: A total of 1476 Gwangju women who attended Chosun University between December 2007 tand April 2010 were enrolled in this study. Bone mineral density (BMD) was determined for the lumbar spine, femoral neck, and total femur by dual-energy X-ray absorptiometry (DXA) using a GE-LUNA Progidy. We excluded women who had conditions that influence bone metabolism. BMD values were expressed in g/cm2 and the T-score. Osteoporosis was defined by a T-score < -2.5 SD for 20-29-year-old Korean adults. Results: The prevalence of osteoporosis in Gwangju women was 19 (12.8%), 19 (12.1%), 95 (18.8%), 158 (42.2%). 97 (74.0%), and 115 (71.7%) at the spine, 0 (0%), 5 (3.4%), 11 (2.2%), 55 (14.7%). 65 (49.6%), and 101 (63.3%) at the femoral neck, and 0 (0%), 3 (1.7%), 3 (0.6%), 11 (2.9%), 22 (16.8%), and 53 (33.3%) for the total femur of the groups 20～29, 30～39, 40～49, 50～59, 60～69, 70～88 years of age, respectively. Conclusion: The criteria for osteoporosis are based on postmenopausal women, but premenopausal women who have low bone mineral density need to be examined for underlying diseases. Further, we must carefully establish a standard for BM for premenopausal women.

참고문헌 (37)

  1. "NIH consensus conference. Osteoporosis prevention, diagnosis, and therapy", JAMA, 285, pp.785~795 (2001)
  2. Cummings SR, "Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group", Lancet, 341, pp.72~75 (1993)
  3. Nevitt MC, "Bone mineral density predicts non-spine fractures in very elderly women. Study of Osteoporotic Fractures Research Group", Osteoporos Int, 4, pp.325~331 (1994)
  4. Kanis JA, "Diagnosis of osteoporosis and assessment of fracture risk", Lancet, 359, pp.1929~1936 (2002)
  5. Heaney RP, "Calcium nutrition and bone health in the elderly", Am J Clin Nurt, 36, pp.986~1013 (1982)
  6. Ongphiphadhanakul B, "Osteoporosis: The Role of Genetics and the Environment", Forum Nutr, 60, pp.158~167 (2007)
  7. Cundy T, "Sources of interracial variation in bone mineral density", J Bone Minor Res, 10(Suppl 3), pp.368~373 (1995)
  8. Russell-Aulet M, "Pierson RN Jr. Bone mineral density and mass in a cross-sectional study of white and Asian women", J Bone Miner Res, 8, pp.575~582 (1993)
  9. Tobias JH, "A comparison of bone mineral density between Caucasian, Asian and Afro-Caribbean women", Clin Sci(Lond), 87(Suppl 5), pp.587~591 (1994)
  10. Kanis JA, "The diagnosis of osteoporosis", J Bone Miner Res, 9(Suppl 8), pp.1137~1141 (1994)
  11. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis, "WHO study group", WHO, 843~ (1994)
  12. Heaney RP, "Calcium nutrition and bone health in the elderly", Am J Clin Nurt, 36(Suppl 5), pp.986~1013 (1982)
  13. "Guidelines for the early detection of osteoporosis and prediction of fracture risk. Council of the National Osteoporosis Foundation", S Afr Med J, 86(Suppl 9), pp.1113~1116 (1996)
  14. Joseph P, "Osteoporosis. Guidelines for general practitioners", Aust Fam Physician, 26(Suppl 10), pp.1181~1196 (1997)
  15. Ross PD, "Epidermiology and consequences of osteoporotic fractures: The Aging Skeleton", pp.339~347 (1999), Academic Press
  16. Bauer DC, "Factors associated with appendicular bone mass in older women. The Study of Osteoporotic Fractures Research Group", Ann Intern Med, 118(9), pp.657~665 (1993)
  17. Cadarette SM, "Development and validation of the Osteoporosis Risk Assessment Instrument to facilitate selection of women for bone densitometry", Can Med Ass J, 162(Suppl 9), pp.1289~1294 (2000)
  18. Lydick E, "Development and validation of a simple questionnaire to facilitate identification of women likely to have low bone density", Am J Manag Care, 4(Suppl 1), pp.37~48 (1998)
  19. Epstein S, "Postmenopausal osteoporosis: fracture consequences and treatment efficacy vary by skeletal site", Aging Clin Exp Res, 12(Suppl 5), pp.330~341 (2000)
  20. Lewiecki EM, "Special report on the official positions of the International Society for Clinical Densitometry", Osteoporos Int, 15(Suppl 10), pp.779~784 (2004)
  21. Khosla S, "Epidemiology and clinical features of osteoporosis in young individuals", Bone, 15(Suppl 5), pp.551~555 (1994)
  22. Cohen A, "Clinical characteristics and medication use among premenopausal women with osteoporosis and low BMD: the experience of an osteoporosis referral center", J Womens Health (Larchmt), 18(Suppl 1), pp.79~84 (2009)
  23. Peris P, "Clinical characteristics and etiologic factors of premenopausal osteoporosis in a group of Spanish women", Semin Arthritis Rheum, 32(Suppl 1), pp.64~70 (2002)
  24. Cummings SR, "Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group", Lancet, 341, pp.72~75 (1993)
  25. Sahli H, "Bone mineral density in healthy Tunisian women", Maturitas, 63(Suppl 3), pp.227~232 (2009)
  26. Slemenda CW, "Assessing fracture risk. In: Osteoporosis", pp.623~633 (1996), Academic Press
  27. Parfitt AM, "Bone Remodeling and Bone Loss: Understanding The Pathophysiology of Osteoporosis", Clin Obstet Gynecol, 30(Suppl 4), pp.789~811 (1987)
  28. Bainbridge KE, "Natural History of Bone Loss over 6 Years among Premenopausal and Early Postmenopausal Women", Am J Epidemiol, 156, pp.410~417 (2002)
  29. Ortolani S, "Spinal and forearm bone mass in relation to ageing and menopause in healthy Italian women", Eur J Clin invest, 21(Suppl 1), pp.33~39 (1991)
  30. Okano H, "The long-term effect of menopause on postmenopausal bone loss in Japanese women: results from a prospective study", J Bone Miner Res, 13(Suppl 2), pp.303~309 (1998)
  31. Arlot ME, "Apparent pre-and postmenopausal bone loss evaluated by DXA at different skeletal sites in women: the OFELY cohort", J Bone Miner Res, 12, pp.683~690 (1997)
  32. Ito M, "Effects of menopause on age-dependent bone loss in the axial and appendicular skeletons in healthy Japanese women", Osteoporos Int, 10(Suppl 5), pp.377~383 (1999)
  33. Iki M, "Relative contributions of age and menopause to the vertebral bone density of healthy Japanese women", Bone, 18(Suppl 6), pp.617~620 (1996)
  34. Cheng XG, "Age-Related Bone Mineral Density, Bone Loss Rate, Prevalence of Osteoporosis, and Reference Database of Women at Multiple Centers in China", Journal of Clinical Densitometry, 10(Suppl 3), pp.276~284 (2007)
  35. Jeon GH, "Prevalence of Osteoporosis and Osteopenia in Women in Kangwoon Province: Geographical Comparison Study", Korean Journal of Bone Metabolism, 15(Suppl 2), pp.135~141 (2008)
  36. Choi JY, "Prevalence and Risk Factors of Osteoporosis and Osteopenia in Korean Women: Cross-sectional Study", The Journal of the Korean Society of Menopause, 14(Suppl 1), pp.35~49 (2008)
  37. 송태종, "폐경 및 폐경 주변기 여성에서 골다공증을예측하는 위험지표들의 유용성", Korean Journal of Obstetrics and Gynecology, 48(11), pp.2627~2634 (2005), 대한산부인과학회

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