Relationship between Serum Dehydroepiandrosterone (DHEA) Concentration and Physical Fitness after an Exercise Training in Postmenopausal Middle-aged Women
0
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
[PURPOSE] The purpose of this study was to analyze the relationship between serum dehydroepiandrosterone (DHEA) concentration and physical fitness after exercise in middle-aged women. [METHODS] Subjects were randomly assigned to yoga and elastic band resistance exercise group (55.21±3.78 yrs, n=11) and non-exercise group (54.10±2.51 yrs, n=7). The exercise group participants performed upper and lower extremity exercise three times per week for 12 weeks. Body weight, height, %fat, serum DHEA concentration, sit-up, grip strength, and one leg stand (with close eyes) were measured on subjects. [RESULTS] Serum DHEA concentration showed an increased trend after exercise training as compared to before exercise training, but no significant difference between before and after exercise training. Also, variables related to physical fitness as sit-up, grip strength, and one leg stand were significantly (p<.05) increased after exercise training as compared to before exercise training. However, serum DHEA concentration and variables related to physical fitness showed no significant relationship. [CONCLUSIONS] Yoga and elastic band resistance exercise training could improve muscular physical fitness, and could be a potential method increasing serum DHEA concentration in middle-aged women, but this possibility is an obscure. In future studies, the intensity of exercise for increasing physical fitness of middle-aged women and the exercise intensity for metabolic function enhancement due to elevated DHEA concentration in blood should be presented differently.
Abstract
[PURPOSE] The purpose of this study was to analyze the relationship between serum dehydroepiandrosterone (DHEA) concentration and physical fitness after exercise in middle-aged women. [METHODS] Subjects were randomly assigned to yoga and elastic band resistance exercise group (55.21±3.78 yrs, n=11) and non-exercise group (54.10±2.51 yrs, n=7). The exercise group participants performed upper and lower extremity exercise three times per week for 12 weeks. Body weight, height, %fat, serum DHEA concentration, sit-up, grip strength, and one leg stand (with close eyes) were measured on subjects. [RESULTS] Serum DHEA concentration showed an increased trend after exercise training as compared to before exercise training, but no significant difference between before and after exercise training. Also, variables related to physical fitness as sit-up, grip strength, and one leg stand were significantly (p<.05) increased after exercise training as compared to before exercise training. However, serum DHEA concentration and variables related to physical fitness showed no significant relationship. [CONCLUSIONS] Yoga and elastic band resistance exercise training could improve muscular physical fitness, and could be a potential method increasing serum DHEA concentration in middle-aged women, but this possibility is an obscure. In future studies, the intensity of exercise for increasing physical fitness of middle-aged women and the exercise intensity for metabolic function enhancement due to elevated DHEA concentration in blood should be presented differently.
참고문헌 (27)
- 안나영, "폐경 전·후 여성의 운동트레이닝 후 체지방률 및 심폐체력 변화 여부에 따른 체력과 대사성 질환 위험요인의 효과 비교", 운동과학, 24(3), pp.253~265 (2015), 한국운동생리학회[DOI]
- Aizawa, K, "Expression of steroidogenic enzymes and synthesis of sex steroid hormones from DHEA in skeletal muscle of rats", American Journal of Physiology Endocrinology, and Metabolism, 292, pp.E577~E584 (2007)
- Allolio, B, "DHEA treatment: myth or reality", Trends in Endocrinology and Metabolism, 13(7), pp.288~294 (2002)
- Borg, G. A. V, "Psychophysical bases of perceived exertion", Medicine and Science in Sports and Exercise, 14, pp.377~381 (1982)
- Di Blasio, A, "Walking training and cortisol to DHEA-S ratio in postmenopausal: An intervention study", Women & Health, 57(1), pp.1~16 (2017)
- Faulkner, J. A, "Age-related changes in the structure and function of skeletal muscles", Clinical Experimental Pharmacology and Physiology, 34, pp.1091~1096 (2007)
- Gasier, H. G, "Cumulative responses of muscle protein synthesis are augmented with chronic resistance exercise training", Acta Physiology (Oxford), 201, pp.381~389 (2011)
- Granger, D. A, "Assessing dehydroepiandrosterone in saliva: a simple radioimmunoassay for use in studies of children, adolescents and adults", Psychoneuroendocrinology, 24, pp.567~579 (1999)
- Kraemer, W. J, "Recovery responses of testosterone, growth hormone, and IGF-1 after resistance exercise", Journal of Applied Physiology, 122, pp.549~558 (2017)
- Labrie, F, "Is dehydroepiandrosterone a hormone", Journal of Endocrinology, 187, pp.169~196 (2005)
- Legrain, S, "Pharmacology and therapeutic effects of dyhydroepiandrosterone in older subjects", Drugs Aging, 20(13), pp.949~967 (2003)
- Longcope, C, "Aromatization of androgens by muscle and adipose tissue in vivo", Journal of Clinical Endocrinology and Metabolism, 46, pp.146~152 (1978)
- Montero-Fernández, N, "Role of exercise on sarcopenia in the elderly", European Journal of Physical Rehabilitation and Medicine, 49, pp.131~143 (2013)
- Morgan, F. M, "Dehydroepiandrosterone sulfate (DHEAS) levels reflect endogenous LH production and response to human chorionic gonadotropin (hCG) challenge in the older female macaque (Macaca fascicularis)", Menopause, 20(3), pp.329~335 (2013)
- Morrow, A. L, "Neuroactive steroid modulators of the stress response", New York Academic Science, 771, pp.257~272 (1995)
- Muller, M, "Endogenous sex hormones and metabolic syndrome in aging men", Journal of Clinical Endocrinology and Metabolism, 90, pp.2618~2623 (2005)
- Pöllänen, E, "Intramuscular sex hormones are associated with skeletal muscle strength and power in women with different hormonal status", Aging Cell, 14, pp.236~248 (2015)
- Pöllänen, E, "Differential influence of peripheral and systemic sex steroids on skeletal muscle quality in pre- and postmenopausal women", Aging Cell, 10, pp.650~660 (2011)
- Rao, K. S, "Antiaging effects of an intensive mind and body therapeutic program through enhancement of telomerase activity and adult stem cell counts", Journal of Stem Cells, 10(2), pp.107~125 (2015)
- Rutkowski, K, "Dehydroepiandrosterone (DHEA): hypes and hopes", Drug, 74(11), pp.1195~1207 (2014)
- Sato, K, "Dioscorea esculenta–induced increase in muscle sex steroid hormones is associated with enhanced insulin sensitivity in a type 2 diabetes rat model", The Official Journal of the Federation of American Societies for Experimental Biology, 31(2), pp.793~801 (2017)
- Sato, K, "Testosterone & DHEA activate the glucose metabolism-related signaling pathway in skeletal muscle", American Journal of Physiology, 294, pp.E961~E968 (2008)
- Sato, K, "Resistance training restores muscle sex steroid hormone steroidogenesis in older men", The Official Journal of the Federation of American Societies for Experimental Biology, 28, pp.1891~1897 (2014)
- Sato, K, "Serum sex steroids and steroidogenesis- related enzyme expression in skeletal muscle during experimental weight gain in men", Diabetes Metabolism, 40, pp.439~444 (2014)
- Siri, S. E, "Techniques for measuring body composition", pp.223~244 (1961), National Academy of Sciences, National Research Counncil
- Vingren, J. L, "Effect of resistance exercise on muscle steroidogenesis", Journal of Applied Physiology, 105, pp.1754~1760 (2008)
- Wend, K, "Tissue-specific effects of loss of estrogen during menopause and aging", Frontier Endocrinology (Lausanne), 3, pp.19~ (2012)
