Reconstruction of Complicated Posterior Maxillary Bone Defects Using Recombinant Human Bone Morphogenetic Protein-2 with Hydroxyapatite and Fibrin Sealant
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In cases of common alveolar bone deficiency in the posterior edentulous maxilla, dental implant treatment can proceed following the reconstruction of the defect through alveolar ridge augmentation and/or maxillary sinus floor augmentation, depending on the specific characteristics of the bone deficiency. However, reconstruction remains challenging in cases of extensive alveolar defects with large bone perforations. The author successfully managed these complicated posterior maxillary bone defects using recombinant human bone morphogenetic protein-2 with hydroxyapatite and fibrin sealant as carriers. This report presents two cases demonstrating the efficacy of this approach.
Abstract
In cases of common alveolar bone deficiency in the posterior edentulous maxilla, dental implant treatment can proceed following the reconstruction of the defect through alveolar ridge augmentation and/or maxillary sinus floor augmentation, depending on the specific characteristics of the bone deficiency. However, reconstruction remains challenging in cases of extensive alveolar defects with large bone perforations. The author successfully managed these complicated posterior maxillary bone defects using recombinant human bone morphogenetic protein-2 with hydroxyapatite and fibrin sealant as carriers. This report presents two cases demonstrating the efficacy of this approach.
참고문헌 (16)
- Keestra JA, "Long-term effects of vertical bone augmentation : a systematic review", J Appl Oral Sci, 24, pp.3~17 (2016)
- Nam JW, "Randomised controlled clinical trial of augmentation of the alveolar ridge using recombinant human bone morphogenetic protein 2with hydroxyapatite and bovine-derived xenografts : comparison of changes in volume", Br J Oral Maxillofac Surg, 55, pp.822~829 (2017)
- Nam JW, "Sinus Floor Augmentation Using Recombinant Human Bone Morphogenetic Protein-2 With Hydroxyapatite : Volume Assessment", J Craniofac Surg, 31, pp.912~915 (2020)
- McKay WF, "A comprehensive clinical review of recombinant human bone morphogenetic protein-2(INFUSE Bone Graft)", Int Orthop, 31, pp.729~734 (2007)
- Nam JW, "Stepwise verification of bone regeneration using recombinant human bone morphogenetic protein-2 in rat fibula model", J Korean Assoc Oral Maxillofac Surg, 43, pp.373~387 (2017)
- Herford AS, "Reconstruction of mandibular continuity defects with bone morphogenetic protein-2(rhBMP-2)", J Oral Maxillofac Surg, 66, pp.616~624 (2008)
- Kelly MP, "Systematic Review and Meta-Analysis of Recombinant Human Bone Morphogenetic Protein-2 in Localized Alveolar Ridge and Maxillary Sinus Augmentation", J Oral Maxillofac Surg, 74, pp.928~939 (2016)
- Nam JW, "Efficacy of hydroxyapatite and fibrin sealant as carriers for bone morphogenetic protein-2in maxillary sinus floor augmentation : a retrospective study", Int J Oral Maxillofac Surg, 53, pp.795~801 (2024)
- Han JJ, "Clinical and radiographic outcomes of dental implant after maxillary sinus floor augmentation with rhBMP-2", hydroxyapatite compared to deproteinized bovine bone, 2022, pp.17, e0273399~
- Yang HJ, "Void space and long-term volumetric changes of maxillary sinus floor augmentation with comparison between hydroxyapatite soaked with bone morphogenetic protein 2and anorganic bovine xenograft alone", J Craniomaxillofac Surg, 47, pp.1626~1632 (2019)
- Kim HJ, "Efficacy of rhBMP-2", Hydroxyapatite on Sinus Floor Augmentation : A Multicenter, Randomized Controlled Clinical Trial, 2015, pp.94, 158S~165S
- Triplett RG, "Pivotal, randomized, parallel evaluation of recombinant human bone morphogenetic protein-2", absorbable collagen sponge and autogenous bone graft for maxillary sinus floor augmentation, 2009, pp.67, 1947~1960
- Kim MS, "Prospective randomized, controlled trial of sinus grafting using Escherichia-coli-produced rhBMP-2 with a biphasic calcium phosphate carrier compared to deproteinized bovine bone", Clin Oral Implants Res, 26, pp.1361~1368 (2015)
- Haidar ZS, "Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair. Part A : Current challenges in BMP delivery", Biotechnol Lett, 31, pp.1817~1824 (2009)
- Mizushima Y, "Injectable porous hydroxyapatite microparticles as a new carrier for protein and lipophilic drugs", J Control Release, 110, pp.260~265 (2006)
- Xie G, "Hydroxyapatite nanoparticles as a controlled-release carrier of BMP-2 : absorption and release kinetics in vitro", J Mater Sci Mater Med, 21, pp.1875~1880 (2010)