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Detailed Electrode Catheter Positioning is Important for the Ablation of Outflow Tract Origin Ventricular Arrhythmias

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Background and Objectives: Electroanatomical mapping using a three-dimensional (3D) system has high accuracy and improves the results of the ablation of outflow tract (OT) premature ventricular contraction (PVC) or ventricular tachycardia (VT) but imposes a considerable economic burden. Here, we compared detailed diagnostic catheterization and 3D mapping system for the ablation of OT PVC/VT. Materials and Methods: Between June 2012 and February 2017, patients with symptomatic OT PVC/VT underwent radiofrequency ablation. Group 1 underwent detailed diagnostic catheterization (using circular and linear multielectrodes) without a 3D mapping system, while group 2 underwent diagnostic catheterization using a conventional 3D mapping system. Procedural success of PVC reduction, remaining symptoms, need for post-operative medications, and procedural time were evaluated. Results: Ninety-eight OT PVC/VT cases were consecutively enrolled. The mean follow-up period was 17.7±14.5 months. Neither acute success rate (95% vs. 82%, p=0.06) nor a PVC reduction > 80% (84% vs. 87%, p=0.74) differed significantly between the two groups. The recurrence rates of PVC-related symptoms were similar (12% vs. 7%, p=0.06) between the groups, but the medication requirement for symptomatic PVC differed (12% vs. 29%, p<0.01). The total procedure time of group 1 was shorter than that of group 2 (132±42 min vs. 157±47 min, p=0.01) and fluoroscopy time (24±15 min vs. 38±22 min, p<0.01) and ablation time (528±538 sec vs. 899±598 sec, p<0.01) were also significantly shortened. Conclusion: Detailed electrode catheter positioning is a safe and cost-effective method for the ablation of OT PVC/VT.

Abstract

Background and Objectives: Electroanatomical mapping using a three-dimensional (3D) system has high accuracy and improves the results of the ablation of outflow tract (OT) premature ventricular contraction (PVC) or ventricular tachycardia (VT) but imposes a considerable economic burden. Here, we compared detailed diagnostic catheterization and 3D mapping system for the ablation of OT PVC/VT. Materials and Methods: Between June 2012 and February 2017, patients with symptomatic OT PVC/VT underwent radiofrequency ablation. Group 1 underwent detailed diagnostic catheterization (using circular and linear multielectrodes) without a 3D mapping system, while group 2 underwent diagnostic catheterization using a conventional 3D mapping system. Procedural success of PVC reduction, remaining symptoms, need for post-operative medications, and procedural time were evaluated. Results: Ninety-eight OT PVC/VT cases were consecutively enrolled. The mean follow-up period was 17.7±14.5 months. Neither acute success rate (95% vs. 82%, p=0.06) nor a PVC reduction > 80% (84% vs. 87%, p=0.74) differed significantly between the two groups. The recurrence rates of PVC-related symptoms were similar (12% vs. 7%, p=0.06) between the groups, but the medication requirement for symptomatic PVC differed (12% vs. 29%, p<0.01). The total procedure time of group 1 was shorter than that of group 2 (132±42 min vs. 157±47 min, p=0.01) and fluoroscopy time (24±15 min vs. 38±22 min, p<0.01) and ablation time (528±538 sec vs. 899±598 sec, p<0.01) were also significantly shortened. Conclusion: Detailed electrode catheter positioning is a safe and cost-effective method for the ablation of OT PVC/VT.

참고문헌 (17)

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  2. Grimm W, "Reversal of tachycardia induced cardiomyopathy following ablation of repetitive monomorphic right ventricular outflow tract tachycardia", Pacing Clin Electrophysiol, 24, pp.166~171 (2001)
  3. Mountantonakis SE, "Reversal of outflow tract ventricular premature depolarization-induced cardiomyopathy with ablation:effect of residual arrhythmia burden and preexisting cardiomyopathy on outcome", Heart Rhythm, 8, pp.1608~1614 (2011)
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  13. Erkapic D, "Ablation of premature ventricular complexes exclusively guided by three-dimensional noninvasive mapping", Card Electrophysiol Clin, 7, pp.109~115 (2015)
  14. Erkapic D, "Clinical impact of a novel threedimensional electrocardiographic imaging for non-invasive mapping of ventricular arrhythmias-a prospective randomized trial", Europace, 17, pp.591~597 (2015)
  15. Jamil-Copley S, "Noninvasive electrocardiographic mapping to guide ablation of outflow tract ventricular arrhythmias", Heart Rhythm, 11, pp.587~594 (2014)
  16. Kesek M, "Entrapment of circular mapping catheter in the mitral valve", Heart Rhythm, 4, pp.17~19 (2007)
  17. Coggins DL, "Radiofrequency catheter ablation as a cure for idiopathic tachycardia of both left and right ventricular origin", J Am Coll Cardiol, 23, pp.1333~1341 (1994)

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