Influence of Sodium Hyaluronate Concentration on Corneal Aberrations in Soft Contact Lens Wearers
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초록
This study aimed to evaluate the influence of varying concentrations of sodium hyaluronate (SH) eyedrops on corneal aberrations in normal individuals wearing silicone hydrogel contact lenses. Methods: Normal individuals wearing silicone hydrogel contact lenses were enrolled in this study. Subjects wereclassified into two groups depending on the concentration of the preservative-free SH used (group 1, 0.1% SH;group 2, 0.3% SH). All subjects were asked to blink five times after instillation of the SH eye drop and beforethe Galilei measurements. Corneal aberrations were measured over the contact lenses before and after SHeye drop instillation. Visual acuity (VA) over the contact lenses was also measured both before instillation ofthe SH eye drop and after the subjects completed the five blinks. Results: There was no change in VA after SH instillation in group 1; however, group 2’s VA significantly deterioratedafter SH instillation. Changes in VA after SH instillation compared to baseline were significantly higherin group 2 than in group 1. Similarly, the increase in corneal aberrations after SH instillation was significant ingroup 2 but not significant in group 1. Among the significantly increased corneal aberration parameters, defocuswas the main type in group 2. Changes in corneal aberrations after SH instillation compared to baselinewere significantly higher in group 2 than in group 1. Conclusions: A 0.3%-concentration of SH increases corneal aberration and decreases VA in soft contact lenswearers. Defocus is the main type of aberration that increased in the 0.3% SH instillation group.
Abstract
This study aimed to evaluate the influence of varying concentrations of sodium hyaluronate (SH) eyedrops on corneal aberrations in normal individuals wearing silicone hydrogel contact lenses. Methods: Normal individuals wearing silicone hydrogel contact lenses were enrolled in this study. Subjects wereclassified into two groups depending on the concentration of the preservative-free SH used (group 1, 0.1% SH;group 2, 0.3% SH). All subjects were asked to blink five times after instillation of the SH eye drop and beforethe Galilei measurements. Corneal aberrations were measured over the contact lenses before and after SHeye drop instillation. Visual acuity (VA) over the contact lenses was also measured both before instillation ofthe SH eye drop and after the subjects completed the five blinks. Results: There was no change in VA after SH instillation in group 1; however, group 2’s VA significantly deterioratedafter SH instillation. Changes in VA after SH instillation compared to baseline were significantly higherin group 2 than in group 1. Similarly, the increase in corneal aberrations after SH instillation was significant ingroup 2 but not significant in group 1. Among the significantly increased corneal aberration parameters, defocuswas the main type in group 2. Changes in corneal aberrations after SH instillation compared to baselinewere significantly higher in group 2 than in group 1. Conclusions: A 0.3%-concentration of SH increases corneal aberration and decreases VA in soft contact lenswearers. Defocus is the main type of aberration that increased in the 0.3% SH instillation group.
참고문헌 (14)
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