High-Intensity Focused Ultrasound Therapy Versus Coblation for the Treatment of Inferior Turbinate Hypertrophy: A Clinical Trial
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Objectives. To compare the efficacy and safety of high-intensity focused ultrasound (HIFU) therapy with coblation for thetreatment of inferior turbinate hypertrophy (ITH). Methods. In this randomized controlled clinical trial, 20 patients underwent inferior turbinate surgery, which consisted ofeither HIFU or coblation therapy. Efficacy, safety, and tolerability were evaluated by subjective symptom scores,acoustic rhinometry, and nasal endoscopy. Results. The modified nasal obstruction symptom evaluation (NOSE) score and nasal obstruction visual analog scale (NO-VAS) significantly decreased in both groups 12 weeks postoperatively. The between-group differences in the evalua-tion scores were not statistically significant. On nasal endoscopy, the HIFU patients showed improvements in mucosalswelling sooner than the patients undergoing coblation therapy. Nasal crusting significantly increased in the patientsundergoing coblation compared to the patients undergoing HIFU therapy until postoperative week 4. Mucosal pres-ervation was superior in the HIFU patients. Although HIFU was less painful than coblation therapy during the proce-dure, the difference was not significant (4.9 vs. 6.3, P =0.143). The difference in global satisfaction between the twogroups was not statistically significant, although satisfaction was slightly higher among the HIFU patients than amongthe coblation patients (4.6 vs. 4.1, P =0.393). Conclusion. HIFU provided results similar to those of coblation therapy for patients with nasal obstruction due to ITH, butHIFU therapy caused less discomfort during the procedure. HIFU therapy appears to be a good noninvasive alterna-tive to the current surgical modalities for ITH.
Abstract
Objectives. To compare the efficacy and safety of high-intensity focused ultrasound (HIFU) therapy with coblation for thetreatment of inferior turbinate hypertrophy (ITH). Methods. In this randomized controlled clinical trial, 20 patients underwent inferior turbinate surgery, which consisted ofeither HIFU or coblation therapy. Efficacy, safety, and tolerability were evaluated by subjective symptom scores,acoustic rhinometry, and nasal endoscopy. Results. The modified nasal obstruction symptom evaluation (NOSE) score and nasal obstruction visual analog scale (NO-VAS) significantly decreased in both groups 12 weeks postoperatively. The between-group differences in the evalua-tion scores were not statistically significant. On nasal endoscopy, the HIFU patients showed improvements in mucosalswelling sooner than the patients undergoing coblation therapy. Nasal crusting significantly increased in the patientsundergoing coblation compared to the patients undergoing HIFU therapy until postoperative week 4. Mucosal pres-ervation was superior in the HIFU patients. Although HIFU was less painful than coblation therapy during the proce-dure, the difference was not significant (4.9 vs. 6.3, P =0.143). The difference in global satisfaction between the twogroups was not statistically significant, although satisfaction was slightly higher among the HIFU patients than amongthe coblation patients (4.6 vs. 4.1, P =0.393). Conclusion. HIFU provided results similar to those of coblation therapy for patients with nasal obstruction due to ITH, butHIFU therapy caused less discomfort during the procedure. HIFU therapy appears to be a good noninvasive alterna-tive to the current surgical modalities for ITH.
참고문헌 (18)
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