피부 및 연조직 감염에서의 항생제 내성 및 최신 치료
Antimicrobial Resistance and Treatment Update of Skin and Soft Tissue Infections
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참고문헌
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초록
피부 및 연조직 감염증의 흔한 원인균은 A군 베타용혈 사슬알균과 황색포도알균이다. 이들 주요 원인 미생물의 항균제 내성 양상은 과거와 비교하여 크게 바뀌지 않았으며, 따라서 피부 및 연조직 감염증의 치료법 역시 이전과 비교하여 크게 바뀌지 않았다. 이 글에서는 현시점에서 추천하는 항생제를 포함한 피부 및 연조직 감염증의 치료 전반을 정리하였다. 아직까지 우리나라에서 문제가 되고 있지 않으나 북미에서 확산되고 있는 CA-MRSA에 의한 피부 및 연조직 감염증 발생 가능성에 대해서는 앞으로도 주목할 필요가 있다고 판단한다.
Abstract
Soft tissue infections are common, generally of mild to moderate severity. The most common causative organisms of soft tissue infections are group A ß-hemolytic streptococci and Staphylococcus aureus. As the antimicrobial resistance pattern of these causative organisms has not been changed recently, the present recommendations for the treatment of soft tissue infections remain the same. In this review, we have presented extensive information on the clinical characteristics, diagnosis, and treatment of skin and soft tissue infections. We focused on two issues concerning antibiotic resistance; macrolide resistance of group A ß-hemolytic streptococci and the emergence of community-acquired methicillin-resistant Staphylococcus aureus. (Korean J Med 2011;81:699-707)
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