Oral signs of acute leukemia for early detection
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Purpose: Systemic disease can manifest oral signs at an early phase, which may be crucialfor the diagnosis and timing of treatment. This report describes two patients who presentedwith gingival enlargement as an early sign of acute leukemia. Methods: Two patients presented with oral symptoms including severe gingival enlargement. The progress of their symptoms was associated with underlying systemic disease. Results: The patients were transferred to the Department of Hematology and diagnosedwith acute myelomonocytic leukemia. They received appropriate treatment and survived. Conclusions: Gingival enlargement can be caused by underlying systemic diseases. Accuratediagnosis and timely referral are important for preventing a fatal situation. It must beemphasized that some oral signs and symptoms may be closely correlated with systemicdiseases.
Abstract
Purpose: Systemic disease can manifest oral signs at an early phase, which may be crucialfor the diagnosis and timing of treatment. This report describes two patients who presentedwith gingival enlargement as an early sign of acute leukemia. Methods: Two patients presented with oral symptoms including severe gingival enlargement. The progress of their symptoms was associated with underlying systemic disease. Results: The patients were transferred to the Department of Hematology and diagnosedwith acute myelomonocytic leukemia. They received appropriate treatment and survived. Conclusions: Gingival enlargement can be caused by underlying systemic diseases. Accuratediagnosis and timely referral are important for preventing a fatal situation. It must beemphasized that some oral signs and symptoms may be closely correlated with systemicdiseases.
참고문헌 (29)
- Wickramasinghe SN, "Blood and bone marrow. 3rd ed" (1986), Churchill Livingston
- Little JW, "Dental management of the medically compromised patient. 6th ed" (2002), Mosby
- Fauci AS, "Harrison's principles of internal medicine. 17th ed" (2008), McGraw-Hill Medical
- 정규원, "Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2011", Cancer Research and Treatment, 46(2), pp.109~123 (2014), 대한암학회
- Bennett JM, "Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group", Ann Intern Med, 103, pp.620~625 (1985)
- Vardiman JW, "The World Health Organization (WHO) classification of the myeloid neoplasms", Blood, 100, pp.2292~2302 (2002)
- Harris NL, "The World Health Organization classification of hematological malignancies report of the Clinical Advisory Committee Meeting, Airlie House, Virginia, November 1997", Mod Pathol, 13, pp.193~207 (2000)
- Demirer S, "Gingival hyperplasia as an early diagnostic oral manifestation in acute monocytic leukemia: a case report", Eur J Dent, 1, pp.111~114 (2007)
- Fatahzadeh M, "Manifestation of acute monocytic leukemia in the oral cavity: a case report", Spec Care Dentist, 28, pp.190~194 (2008)
- Reenesh M, "Generalised leukaemic gingival enlargement: a case report", J Oral Maxillofac Res, 3, pp.e5~ (2012)
- Wu J, "Oral manifestations of acute myelomonocytic leukemia: a case report and review of the classification of leukemias", J Periodontol, 73, pp.664~668 (2002)
- Felix DE, "Oral symptoms as a chief sign of acute monoblastic leukemia: report of case", J Am Dent Assoc, 113, pp.899~900 (1986)
- Hou GL, "Primary gingival enlargement as a diagnostic indicator in acute myelomonocytic leukemia. A case report", J Periodontol, 59, pp.852~855 (1988)
- McKenna SJ, "Leukemia", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 89, pp.137~139 (2000)
- Brazelton J, "Temporomandibular joint arthritis as an initial presentation of acute myeloid leukemia with myelodysplasia-related changes: a report of an unusual case", J Oral Maxillofac Surg, 72, pp.1677~1683 (2014)
- Chung SW, "Osteolytic mandible presenting as an initial manifestation of an adult acute lymphoblastic leukaemia", Int J Oral Maxillofac Surg, 40, pp.1438~1440 (2011)
- Stafford R, "Oral pathoses as diagnostic indicators in leukemia", Oral Surg Oral Med Oral Pathol, 50, pp.134~139 (1980)
- Estey E, "Acute myeloid leukaemia", Lancet, 368, pp.1894~1907 (2006)
- Bergmann OJ, "Isolated gingival relapse in acute myeloid leukaemia", Eur J Haematol, 40, pp.473~476 (1988)
- Carranza FA, "Carranza`s clinical periodontology. 10th ed" (2006), Saunders Elsevier
- Abdullah BH, "Gingival fine needle aspiration cytology in acute leukemia", J Oral Pathol Med, 31, pp.55~58 (2002)
- Weckx LL, "Oral manifestations of leukemia", Ear Nose Throat J, 69, pp.341~342 (1990)
- Dreizen S, "Malignant gingival and skin "infiltrates" in adult leukemia", Oral Surg Oral Med Oral Pathol, 55, pp.572~579 (1983)
- Hou GL, "Analysis of oral manifestations of leukemia: a retrospective study", Oral Dis, 3, pp.31~38 (1997)
- Angst PD, "Periodontal status and its correlation with haematological parameters in patients with leukaemia", J Clin Periodontol, 39, pp.1003~1010 (2012)
- Peterson DE, "Dental management of leukemic patients", Oral Surg Oral Med Oral Pathol, 47, pp.40~42 (1979)
- Stoopler ET, "Medical management update: multiple myeloma", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 103, pp.599~609 (2007)
- Mawardi H, "Medical management update: non-Hodgkin lymphoma", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 107, pp.e19~e33 (2009)
- Heimdahl A, "Prevention and management of oral infections in cancer patients", Support Care Cancer, 7, pp.224~228 (1999)