Bicuspid Aortic Valve: Unresolved Issues and Role of Imaging Specialists
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초록
Bicuspid aortic valve (BAV) is the most common congenital heart disease with marked heterogeneity in many aspects. Fusionpatterns of the aortic cusp are quite variable with different type and severity of valvular dysfunction. Moreover, non-valvularcardiovascular abnormalities are associated with BAV. Among them, aortic aneurysm/dissection is the most serious clinicalcondition with variable patterns of segmental aortic dilatation. Potential association between BAV phenotype and valvulopathyor aortopathy has been suggested, but needs to be tested further. A lack of long-term outcome data at this moment is responsiblefor unresolved debate regarding appropriate management of patients with BAV, specifically to prevent development of aorticdissection. Long-term follow-up data of a well-characterized cohort or registry based on standardized classification of BAVphenotype and aortopathy are necessary for evidence-based medical practice. Advanced imaging techniques such as computedtomography or magnetic resonance imaging offer better opportunities for accurate phenotype classification and imagingspecialists should play a central role to establish a collaborative multicenter cohort or registry.
Abstract
Bicuspid aortic valve (BAV) is the most common congenital heart disease with marked heterogeneity in many aspects. Fusionpatterns of the aortic cusp are quite variable with different type and severity of valvular dysfunction. Moreover, non-valvularcardiovascular abnormalities are associated with BAV. Among them, aortic aneurysm/dissection is the most serious clinicalcondition with variable patterns of segmental aortic dilatation. Potential association between BAV phenotype and valvulopathyor aortopathy has been suggested, but needs to be tested further. A lack of long-term outcome data at this moment is responsiblefor unresolved debate regarding appropriate management of patients with BAV, specifically to prevent development of aorticdissection. Long-term follow-up data of a well-characterized cohort or registry based on standardized classification of BAVphenotype and aortopathy are necessary for evidence-based medical practice. Advanced imaging techniques such as computedtomography or magnetic resonance imaging offer better opportunities for accurate phenotype classification and imagingspecialists should play a central role to establish a collaborative multicenter cohort or registry.
참고문헌 (36)
- Roberts WC., "The congenitally bicuspid aortic valve. A study of 85 autopsy cases", Am J Cardiol, 26, pp.72~83 (1970)
- Basso C, "An echocardiographic survey of primary school children for bicuspid aortic valve", Am J Cardiol, 93, pp.661~663 (2004)
- Nistri S, "Frequency of bicuspid aortic valve in young male conscripts by echocardiogram", Am J Cardiol, 96, pp.718~721 (2005)
- Siu SC, "Bicuspid aortic valve disease", J Am Coll Cardiol, 55, pp.2789~2800 (2010)
- Michelena HI, "Bicuspid aortic valve : identifying knowledge gaps and rising to the challenge from the International Bicuspid Aortic Valve Consortium(BAVCon)", Circulation, 129, pp.2691~2704 (2014)
- Schaefer BM, "The bicuspid aortic valve : an integrated phenotypic classification of leaflet morphology and aortic root shape", Heart, 94, pp.1634~1638 (2008)
- Buchner S, "Variable phenotypes of bicuspid aortic valve disease : classification by cardiovascular magnetic resonance", Heart, 96, pp.1233~1240 (2010)
- Kang JW, "Association between bicuspid aortic valve phenotype and patterns of valvular dysfunction and bicuspid aortopathy : comprehensive evaluation using MDCT and echocardiography", JACC Cardiovasc Imaging, 6, pp.150~161 (2013)
- Fernández B, "Bicuspid aortic valves with different spatial orientations of the leaflets are distinct etiological entities", J Am Coll Cardiol, 54, pp.2312~2318 (2009)
- Fernandes SM, "Morphology of bicuspid aortic valve in children and adolescents", J Am Coll Cardiol, 44, pp.1648~1651 (2004)
- Fernandes SM, "Bicuspid aortic valve morphology and interventions in the young", J Am Coll Cardiol, 49, pp.2211~2214 (2007)
- Braverman AC, "Aortic involvement in patients with a bicuspid aortic valve", Heart, 97, pp.506~513 (2011)
- Michelena HI, "Incidence of aortic complications in patients with bicuspid aortic valves", JAMA, 306, pp.1104~1112 (2011)
- Kim YG, "Aortopathy and bicuspid aortic valve : haemodynamic burden is main contributor to aortic dilatation", Heart, 98, pp.1822~1827 (2012)
- Hahn RT, "stenotic and functionally normal bicuspid aortic valves", J Am Coll Cardiol, 19, pp.283~288 (1992)
- Keane MG, "Bicuspid aortic valves are associated with aortic dilatation out of proportion to coexistent valvular lesions", Circulation, 102(19), pp.35~39 (2000)
- Beroukhim RS, "Progression of aortic dilation in children with a functionally normal bicuspid aortic valve", Am J Cardiol, 98, pp.828~830 (2006)
- Della Corte A, "Predictors of ascending aortic dilatation with bicuspid aortic valve: a wide spectrum of disease expression", Eur J Cardiothorac Surg, pp.397~404 (2007)
- Yasuda H, "Failure to prevent progressive dilation of ascending aorta by aortic valve replacement in patients with bicuspid aortic valve: comparison with tricuspid aortic valve", Circulation, 108(1), pp.291~294 (2003)
- Huntington K, "A prospective study to assess the frequency of familial clustering of congenital bicuspid aortic valve", J Am Coll Cardiol, 30, pp.1809~1812 (1997)
- Cripe L, "Bicuspid aortic valve is heritable", J Am Coll Cardiol, 44, pp.138~143 (2004)
- Garg V, "Mutations in NOTCH1 cause aortic valve disease", Nature, 437, pp.270~274 (2005)
- Mohamed SA, "Novel missense mutations (p.T596M and p.P1797H) in NOTCH1 in patients with bicuspid aortic valve", Biochem Biophys Res Commun, 345, pp.1460~1465 (2006)
- Forte A, "Early cell changes and TGFβ pathway alterations in the aortopathy associated with bicuspid aortic valve stenosis", Clin Sci (Lond), 124, pp.97~108 (2013)
- Charitos EI, "The fate of the bicuspid valve aortopathy after aortic valve replacement", Eur J Cardiothorac Surg, 45, pp.128~135 (2014)
- Kari FA, "Bicuspid aortic valve configuration and aortopathy pattern might represent different pathophysiologic substrates", J Thorac Cardiovasc Surg, 144, pp.516~517 (2012)
- Della Corte A, "The ascending aorta with bicuspid aortic valve : a phenotypic classification with potential prognostic significance", Eur J Cardiothorac Surg, 46, pp.240~247 (2014)
- Hope MD, "Bicuspid aortic valve : four-dimensional MR evaluation of ascending aortic systolic flow patterns", Radiology, 255, pp.53~61 (2010)
- Mahadevia R, "Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy", Circulation, 129, pp.673~682 (2014)
- Michelena HI, "Natural history of asymptomatic patients with normally functioning or minimally dysfunctional bicuspid aortic valve in the community", Circulation, 117, pp.2776~2784 (2008)
- Tzemos N, "Outcomes in adults with bicuspid aortic valves", JAMA, 300, pp.1317~1325 (2008)
- Hardikar AA, "Surgical thresholds for bicuspid aortic valve associated aortopathy", JACC Cardiovasc Imaging, 6, pp.1311~1320 (2013)
- Kallenbach K, "Aortic surgery for ascending aortic aneurysms under 5.0 cm in diameter in the presence of bicuspid aortic valve", JACC Cardiovasc Imaging, 6, pp.1321~1326 (2013)
- Verma S, "Knowledge, attitudes, and practice patterns in surgical management of bicuspid aortopathy: a survey of 100 cardiac surgeons", J Thorac Cardiovasc Surg, 146, pp.1033~1040 (2013)
- Barker AJ, "Bicuspid aortic valve phenotype and aortopathy : nomenclature and role of aortic hemodynamics", JACC Cardiovasc Imaging, 6, pp.921~ (2013)
- Della Corte A., "Phenotypic heterogeneity of bicuspid aortopathy: a potential key to decode the prognosis?", Heart, 100, pp.96~97 (2014)