본문 바로가기
KERD
논문KCI 등재

The Change of Prostate Cancer Treatment in Korea: 5 Year Analysis of a Single Institution

2

조회

0

다운로드

12

인용

0

참고문헌

키워드

주제분류의학일반

초록

Purpose: We analyzed changes to the trends of prostate cancer management and patient characteristics at a single institute during 5 years due to the significant increase of the prostate cancer incidence and the robotic equipment in Korea. Materials and Methods: Prostate cancer patient data from a single institute recorded from 2006 to 2010 were analyzed. Cancer stage, initial treatment modalities, and the pattern of outpatient clinical management were reviewed. Results: Between 2006 and 2010, 386 prostate cancers were newly diagnosed at the institute. The proportion of localized and locally advanced cancer cases increased from 67% in 2006 to 79% in 2010 respectively. Among the treatment choices during follow-up in the out-patients clinic, the proportion of radical prostatectomies increased from 43% in 2006 to 62% in 2010. In contrast, the proportion of hormone therapies decreased from 58% to 37%. For initial treatment choice, radical prostatectomy was chosen for 59% of the patients who were newly diagnosed with cancer during the study period. However, hormone therapy alone was administrated as a primary therapy to 26%. Analysis of the radical prostatectomy subgroup showed that a robot-assisted technique was used in 83% of the patients, and the remaining 17% underwent an open radical prostatectomy. Conclusion: As the prostate cancer incidence increased in Korea, the proportion of localized and locally advanced cancer also increased. In addition, the main treatment modality changed from non-surgical treatment to radical prostatectomy.

Abstract

Purpose: We analyzed changes to the trends of prostate cancer management and patient characteristics at a single institute during 5 years due to the significant increase of the prostate cancer incidence and the robotic equipment in Korea. Materials and Methods: Prostate cancer patient data from a single institute recorded from 2006 to 2010 were analyzed. Cancer stage, initial treatment modalities, and the pattern of outpatient clinical management were reviewed. Results: Between 2006 and 2010, 386 prostate cancers were newly diagnosed at the institute. The proportion of localized and locally advanced cancer cases increased from 67% in 2006 to 79% in 2010 respectively. Among the treatment choices during follow-up in the out-patients clinic, the proportion of radical prostatectomies increased from 43% in 2006 to 62% in 2010. In contrast, the proportion of hormone therapies decreased from 58% to 37%. For initial treatment choice, radical prostatectomy was chosen for 59% of the patients who were newly diagnosed with cancer during the study period. However, hormone therapy alone was administrated as a primary therapy to 26%. Analysis of the radical prostatectomy subgroup showed that a robot-assisted technique was used in 83% of the patients, and the remaining 17% underwent an open radical prostatectomy. Conclusion: As the prostate cancer incidence increased in Korea, the proportion of localized and locally advanced cancer also increased. In addition, the main treatment modality changed from non-surgical treatment to radical prostatectomy.

참고문헌 (18)

  1. Parkin DM, "Global cancer statistics", CA Cancer J Clin, 49, pp.33~64 (1999)
  2. Sim HG, "Changing demography of prostate cancer in Asia", Eur J Cancer, 41, pp.834~845 (2005)
  3. "Statistics Korea"[URL]
  4. 정규원, "Cancer Statistics in Korea: Incidence, Mortality and Survival in 2006-2007", Journal of Korean Medical Science, 25(8), pp.1113~1121 (2010), 대한의학회
  5. Park SK, "Rising prostate cancer rates in South Korea", Prostate, 66, pp.1285~1291 (2006)
  6. Dasgupta P, "The current status of robot-assisted radical prostatectomy", Asian J Androl, 11, pp.90~93 (2009)
  7. Sung ER, "The “halo effect” in Korea: change in practice patterns since the introduction of robot-assisted laparoscopic radical prostatectomy", J Robotic Surg, 3, pp.57~60 (2009)
  8. "National Evidence-based healthcare collaborating Agency (NECA), Korea"[URL]
  9. "National health insurance system"[URL]
  10. Akaza H, "The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE", J Urol, 176(6), pp.S47~S49 (2006)
  11. Hamilton AS, "Trends in the treatment of localized prostate cancer using supplemented cancer registry data", BJU Int, 107, pp.576~584 (2011)
  12. McVey GP, "Initial management of low-risk localized prostate cancer in the UK: analysis of the British Association of Urological Surgeons Cancer Registry", BJU Int, 106, pp.1161~1164 (2010)
  13. Akaza H, "Trends in primary androgen depletion therapy for patients with localized and locally advanced prostate cancer: Japanese perspective", Cancer Sci, 97, pp.243~247 (2006)
  14. Hinotsu S, "Current status of endocrine therapy for prostate cancer in Japan analysis of primary androgen deprivation therapy on the basis of data collected by J-CaP", Jpn J Clin Oncol, 37, pp.775~781 (2007)
  15. "NCCN clinical practice guidelines in oncology: Asia consensus statement: prostate cancer"[URL]
  16. Cooperberg MR, "Time trends and local variation in primary treatment of localized prostate cancer", J Clin Oncol, 28, pp.1117~1123 (2010)
  17. Lubeck DP, "The CaPSURE database: a methodology for clinical practice and research in prostate cancer. CaPSURE Research Panel. Cancer of the Prostate Strategic Urologic Research Endeavor", Urology, 48, pp.773~777 (1996)
  18. Akaza H, "Characteristics of patients with prostate cancer who have initially been treated by hormone therapy in Japan: J-CaP surveillance", Jpn J Clin Oncol, 34, pp.329~336 (2004)

관련 논문AI추천

Changing Patterns of Primary Treatment in Korean Men with Prostate Cancer Over 10 Years: A Nationwide Population Based Study박진성, 서범석, 신동욱, 안한종, 홍준혁대한암학회 · Cancer Research and Treatment2016 · 제48권 제3호Recent Changes in the Clinicopathologic Features of Korean Men with Prostate Cancer: A Comparison with Western Populations변석수, 서성일, 송채린, 안한종, 이상은, 이상철, 이은식, 이현무, 조진선, 최영득, 최한용연세대학교의과대학 · Yonsei Medical Journal2012 · 제53권 제3호Trends in Prostate Cancer Prevalence and Radical Prostatectomy Rate according to Age Structural Changes in South Korea between 2005 and 2015김재헌, 두승환, 박수연, 송윤섭, 양원재, 이현영연세대학교의과대학 · Yonsei Medical Journal2019 · 제60권 제3호Comparison of Surgical Outcomes of Radical Prostatectomy Using the Multicenter Korean Prostate Cancer Registry (KPCR) Database김청수, 변석수, 서성일, 유성혜, 이지열, 정창욱, 최문주, 최인영, 홍준혁한국보건정보통계학회 · 보건정보통계학회지2018 · 제43권 제3호A Nationwide Study of Differences in Surgical Treatment Rates and Oncological Outcomes for Prostate Cancer according to Economic Status and Region정현, 손환철, 오소희, 유상준, 조민철대한암학회 · Cancer Research and Treatment2023 · 제55권 제2호Cancer-Specific Mortality among Korean Men with Localized or Locally Advanced Prostate Cancer Treated with Radical Prostatectomy Versus Radiotherapy: A Multi-center Study Using Propensity Scoring and Competing Risk Regression Analyses구교철, 김선일, 김세중, 나군호, 방우진, 이승환, 정병하, 조성용, 조진선, 홍성준대한암학회 · Cancer Research and Treatment2018 · 제50권 제1호

이 간행물의 다른 논문 (22건)