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개정된 미국수면의학회 판독 기준이 무호흡 및 저호흡 지수에 미치는 영향

Influences of the Revised American Academy of Sleep Medicine Criteria for Scoring Apnea and Hypopnea on the Apnea-Hypopnea Index

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Objectives: The definition of accurate recording and measuring of sleep related obstructive breathing events are clinically critical as a base for quantifying disease severity in obstructive sleep apnea (OSA) syndrome. The aim of the study was to compare apnea and hypopnea indices using different scoring recommendations. Methods: We retrospectively selected total 60 patients who were diagnosed with OSA syndrome. All sleep-related parameters including apnea index, hypopnea index, and apnea-hypopnea index (AHI) were measured by two different criteria; 1999 Chicago criteria and 2007 American Academy of Sleep Medicine (AASM) criteria for scoring respiratory events. Results: Apnea index and AHI by Chicago criteria were significantly higher than those by AASM criteria (mean 21.0/hr vs. 15.1/hr, p<0.001; mean 36.8/hr vs. 29.4/hr, p<0.001, respectively). But hypopnea index was not different between two criteria. Bland-Altman plots demonstrated a median (5th, 95th percentiles) reduction of 6.1/h (0.16, 20.57) when comparing AHI by AASM criteria to AHI by Chicago criteria. Conclusions: Our results suggested that AASM criteria intended to diagnose more confirmative OSA patients than Chicago criteria. Updated criteria may be stricter but possibly rule out mild OSA patients.

Abstract

Objectives: The definition of accurate recording and measuring of sleep related obstructive breathing events are clinically critical as a base for quantifying disease severity in obstructive sleep apnea (OSA) syndrome. The aim of the study was to compare apnea and hypopnea indices using different scoring recommendations. Methods: We retrospectively selected total 60 patients who were diagnosed with OSA syndrome. All sleep-related parameters including apnea index, hypopnea index, and apnea-hypopnea index (AHI) were measured by two different criteria; 1999 Chicago criteria and 2007 American Academy of Sleep Medicine (AASM) criteria for scoring respiratory events. Results: Apnea index and AHI by Chicago criteria were significantly higher than those by AASM criteria (mean 21.0/hr vs. 15.1/hr, p<0.001; mean 36.8/hr vs. 29.4/hr, p<0.001, respectively). But hypopnea index was not different between two criteria. Bland-Altman plots demonstrated a median (5th, 95th percentiles) reduction of 6.1/h (0.16, 20.57) when comparing AHI by AASM criteria to AHI by Chicago criteria. Conclusions: Our results suggested that AASM criteria intended to diagnose more confirmative OSA patients than Chicago criteria. Updated criteria may be stricter but possibly rule out mild OSA patients.

참고문헌 (10)

  1. "Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force", Sleep, 22, pp.667~689 (1999)
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  5. Iber C, "The AASM manual for the scoring of sleep and associated event: rules, terminology and technical specifications" (2007), American Academy of Sleep Medicine
  6. Ruehland WR, "The new AASM criteria for scoring hypopneas: impact on the hypopnea index", Sleep, 32, pp.150~157 (2009)
  7. 김지언, "폐쇄성 수면무호흡증후군의 진단", Journal of sleep medicine, 3(1), pp.29~33 (2006), 대한수면연구학회
  8. Redline S, "Effects of varying approaches for identifying respiratory disturbances on sleep apnea assessment", Am J Respir Crit Care Med, 161, pp.369~374 (2000)
  9. Yun CH, "Diagnosis and treatment of obstructive sleep apnea syndrome", Korea Sleep Research Soc, 1, pp.34~40 (2004)
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