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Is Split-Night Polysomnography Valid for Women with Obstructive Sleep Apnea?

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Objectives: Split-night polysomnography (PSG) can be used for the diagnosis and treatment of obstructive sleep apnea (OSA). Recently, the American Academy of Sleep Medicine has broadened the indication of split-night PSG from severe to moderate OSA in a time window of 2 hours. However, majority pieces of evidence have been derived from the male predominant study population. The objective of this study was to investigate the diagnostic accuracy of split-night PSG in Korean women. Methods: This study included 122 adult women with OSA. Apnea-hypopnea index (AHI) from the first 120 minutes of clock time (T120- AHI) and full-night AHI (FN-AHI) were compared using the concordance correlation coefficient (CCC) method and Bland-Altman plot. Receiver operating characteristic (ROC) curves and the area under the ROC curves were plotted with various cut-off points of AHI. Results: The T120-AHI correlated with FNAHI (CCC=0.77). The area under the ROC curve for T120-AHI with FN-AHI ≥15 was 0.865, with a sensitivity of 78.6% and specificity of 82.7%. Conclusions: T120-AHI showed a significant correlation with the FN-AHI value in Korean female patients with OSA.

Abstract

Objectives: Split-night polysomnography (PSG) can be used for the diagnosis and treatment of obstructive sleep apnea (OSA). Recently, the American Academy of Sleep Medicine has broadened the indication of split-night PSG from severe to moderate OSA in a time window of 2 hours. However, majority pieces of evidence have been derived from the male predominant study population. The objective of this study was to investigate the diagnostic accuracy of split-night PSG in Korean women. Methods: This study included 122 adult women with OSA. Apnea-hypopnea index (AHI) from the first 120 minutes of clock time (T120- AHI) and full-night AHI (FN-AHI) were compared using the concordance correlation coefficient (CCC) method and Bland-Altman plot. Receiver operating characteristic (ROC) curves and the area under the ROC curves were plotted with various cut-off points of AHI. Results: The T120-AHI correlated with FNAHI (CCC=0.77). The area under the ROC curve for T120-AHI with FN-AHI ≥15 was 0.865, with a sensitivity of 78.6% and specificity of 82.7%. Conclusions: T120-AHI showed a significant correlation with the FN-AHI value in Korean female patients with OSA.

참고문헌 (28)

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