생체활성 Ca10(PO4)6(OH)2/CaSiO3계 복합재료의 제조
Fabrication of Bioactive Ca10(PO4)6(OH)2/CaSiO3 Composites
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Hydroxyapatite (Ca10(PO4)6(OH)2) is a superior biocompatible ceramics, but it also has low bioactivity in the body. On the other hand, wollastonite (CaSiO3) has high bioactivity and low biostability. To obtain the biocomposites having both bioactivity and biostability of two kinds of biomaterials, mixed powder of Ca10(PO4)6(OH)2 and CaSiO3 were prepared by a ball milling and dense compacts were fabricated by sintering at 1250 oC for 1h. Three compositions of biocompositions of biocomposite (7:3, 5:5, 3:7) were chosen by the mixing ratio of hydroxyapatite and wollastonite, respectively. Sintered biocomposites had porous and homogeneous microstucture with the relative density about 57~61%, and the particle size of 1~5 μm. From in vitro test in SBF solution, HA-precipitated particles were observed on the surfaces of biocomposite and pure wollasonite indicating the bioactive properties, but HA-precipitated particles could not observed on the surface of pure sintered hydroxyapatite from in vitro test in SBF solution for 14 days.
Abstract
Hydroxyapatite (Ca10(PO4)6(OH)2) is a superior biocompatible ceramics, but it also has low bioactivity in the body. On the other hand, wollastonite (CaSiO3) has high bioactivity and low biostability. To obtain the biocomposites having both bioactivity and biostability of two kinds of biomaterials, mixed powder of Ca10(PO4)6(OH)2 and CaSiO3 were prepared by a ball milling and dense compacts were fabricated by sintering at 1250 oC for 1h. Three compositions of biocompositions of biocomposite (7:3, 5:5, 3:7) were chosen by the mixing ratio of hydroxyapatite and wollastonite, respectively. Sintered biocomposites had porous and homogeneous microstucture with the relative density about 57~61%, and the particle size of 1~5 μm. From in vitro test in SBF solution, HA-precipitated particles were observed on the surfaces of biocomposite and pure wollasonite indicating the bioactive properties, but HA-precipitated particles could not observed on the surface of pure sintered hydroxyapatite from in vitro test in SBF solution for 14 days.
참고문헌 (10)
- C. Y. Kim, , J. Kor. Ceram. Soc., 10(5), pp.437~447 (1995)
- G. I. Jung, , K. I. C. News, 13, pp.18~31 (2010)
- J. L. Ong, , Crit. Rev. Biomed. Eng., 28, pp.667~707 (2000)
- H. Cao, , Int. J. Appl. Ceram. Technol, 10, pp.1~10 (2013)
- R. Shao, , J. Ceram. Soc. Jpn, 123, pp.17~20 (2015)
- S. Ni, , J. Biomater. Appl, 24, pp.139~158 (2009)
- Y. G. Kim, , Appl. Surf. Sci., 255, pp.589~592 (2008)
- M. A. Sainz, , Acta Biomater, 6, pp.2797~2807 (2010)
- W. L. Suchanek, , Biomaterials, 25, pp.4647~4657 (2004)
- H. S. Ahn, , J. Kor. Ceram. Soc, 36, pp.10~ (1999)