Human Cases of Fascioliasis in Fujian Province, China
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Fascioliasis is a foodborne zoonotic parasitic disease. We report 4 cases occurring in the same family, in whom diagnosis of acute fascioliasis was established after series of tests. One case was hospitalized with fever, eosinophilia, and hepatic lesions. MRI showed hypodense changes in both liver lobes. The remaining 3 cases presented with the symptom of stomachache only. Stool analysis was positive for Fasciola eggs in 2 adult patients. The immunological test and molecular identification of eggs were confirmed at the National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, China. The results of serological detection were positive in all the 4 patients. DNA sequencing of PCR products of the eggs demonstrated 100% homology with ITS and cox1 of Fasciola hepatica. The conditions of the patients were not improved by broad-spectrum anti-parasitic drugs until administration of triclabendazole.
Abstract
Fascioliasis is a foodborne zoonotic parasitic disease. We report 4 cases occurring in the same family, in whom diagnosis of acute fascioliasis was established after series of tests. One case was hospitalized with fever, eosinophilia, and hepatic lesions. MRI showed hypodense changes in both liver lobes. The remaining 3 cases presented with the symptom of stomachache only. Stool analysis was positive for Fasciola eggs in 2 adult patients. The immunological test and molecular identification of eggs were confirmed at the National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, China. The results of serological detection were positive in all the 4 patients. DNA sequencing of PCR products of the eggs demonstrated 100% homology with ITS and cox1 of Fasciola hepatica. The conditions of the patients were not improved by broad-spectrum anti-parasitic drugs until administration of triclabendazole.
참고문헌 (34)
- Mas-Coma S, "Fascioliasis and other plant-borne trematode zoonoses", Int J Parasitol, 35, pp.1255~1278 (2005)
- Mas-Coma S, "Fascioliasis", Adv Exp Med Biol, 766, pp.77~114 (2014)
- Mas-Coma S, "Chapter 2. Fasciola, lymnaeids and human fascioliasis, with a global overview on disease transmission, epidemiology, evolutionary genetics, molecular epidemiology and control", Adv Parasitol, 69, pp.41~146 (2009)
- Ah Jin Kim, "Ectopic Human Fasciola hepatica Infection by an Adult Worm in the Mesocolon", The Korean Journal of Parasitology, 53(6), pp.725~730 (2015), 대한기생충학ㆍ열대의학회
- Qureshi AW, "Epidemiological analysis of human fascioliasis in northeastern Punjab, Pakistan", Acta Trop, 156, pp.157~164 (2016)
- Fürst T, "Global burden of human food-borne trematodiasis : a systematic review and meta-analysis", Lancet Infect Dis, 12, pp.210~221 (2012)
- Mas-Coma S, "Neurological and ocular fascioliasis in humans", Adv Parasitol, 84, pp.27~149 (2014)
- Valero MA, "Higher physiopathogenicity by Fasciola gigantica than by the genetically close F. hepatica: experimental long-term follow-up of biochemical markers", Trans R Soc Trop Med Hyg, 110, pp.55~66 (2016)
- Dalton JP, "Immunomodulatory molecules of Fasciola hepatica : candidates for both vaccine and immunotherapeutic development", Vet Parasitol, 195, pp.272~285 (2013)
- Gironès N, "Immune suppression in advanced chronic fascioliasis : an experimental study in a rat model", J Infect Dis, 195, pp.1504~1512 (2007)
- World Health Organization, "Fact sheet on fascioliasis. In Action Against Worms", World Health Organization, 1~8 (2008)
- Gil LC, "Resistant human fasciolasis: report of four patients", Rev Med Chil, 142, pp.1330~1333 (2014)
- Chen JZ, "Human infections with Fasciola hepatica and Fasciola gigantica in Hainan province", Chin J Parasitol Parasit Dis, 12, pp.243~ (1994)
- Fan D, "CT features of liver abscesses caused by the Fasciola hepatica infection", Chin J Radiol, 40, pp.191~194 (2006)
- Huang ZM, "Report on a patient infected with Fasciola hepatica", Chin Trop Med, 16, pp.1624~ (2006)
- Huang ZM, "Two cases of fascioliasis hepatica", Parasit Infect Dis, 7, pp.172~ (2009)
- Chen JX, "An Outbreak of human fascioliasis gigantica in Southwest China", PLoS One, 8, pp.e71520~ (2013)
- Chen MX, "Parasitological and molecular detection on a young man of human fasciolosis diagnosed in Guizhou, China", Trop Biomed (2017)
- Valero MA, "Assessing the validity of an ELISA test for the serological diagnosis of human fascioliasis in different epidemiological situations", Trop Med Int Health, 17, pp.630~636 (2012)
- Suhardono, "Variations in the survival of Fasciola gigantica eggs in bovine dung stored in the sun as opposed to the shade", Trop Anim Health Prod, 38, pp.379~382 (2006)
- Ai L, "Specific PCR-based assays for the identification of Fasciola species: their development, evaluation and potential usefulness in prevalence surveys", Ann Trop Med Parasitol, 104, pp.65~72 (2010)
- Luton K, "Comparisons of ribosomal internal transcribed spacers from two congeneric species of flukes(Platyhelminthes : Trematoda : Digenea)", Mol Biochem Parasitol, 56, pp.323~327 (1992)
- Bowles J, "Genetic variants within the genus Echinococcus identified by mitochondrial DNA sequencing", Mol Biochem Parasitol, 54, pp.165~173 (1992)
- Soliman MF, "Epidemiological review of human and animal fascioliosis in Egypt", J Infect Dev Ctries, 2, pp.182~189 (2008)
- Saba R, "Human fascioliosis", Clin Microbiol Infect, 10, pp.385~387 (2004)
- Dauchy FA, "Eight cases of fascioliosis : clinical and microbiological features", Med Mal Infect, 36, pp.42~46 (2006)
- Pavlović M, "Human case of fasciolosis in Serbia treated with triclabendazole", Vojnosanit Pregl, 71, pp.202~206 (2014)
- Kozat S, "Glucose, lipid, and lipoprotein levels in sheep naturally infected with Fasciola hepatica", J Parasitol, 96, pp.657~659 (2010)
- Mas-Coma S, "Diagnosis of human fascioliasis by stool and blood techniques : update for the present global scenario", Parasitology, 141, pp.1918~1946 (2014)
- Espino AM, "Dynamics of antigenemia and coproantigens during a human Fasciola hepatica outbreak", J Clin Microbiol, 36, pp.2723~2726 (1998)
- Pagola Serrano MA, "Computed tomography of hepatic fascioliosis", J Comput Assist Tomog, 11, pp.269~272 (1987)
- Patel NU, "CT findings of human Fasciola hepatica infection: case reports and review of the literature", Clin Imaging, 40, pp.251~255 (2016)
- Roig GV, "Hepatic fascioliasis in the Americas: a new challenge for therapeutic endoscopy", Gastrointest Endosc, 56, pp.315~317 (2002)
- Marcos LA, "Natural history, clinicoradiologic correlates, and response to triclabendazole in acute massive fasciolosis", Am J Trop Med Hyg, 78, pp.222~227 (2008)