A Case of Probable Mixed-Infection with Clonorchis sinensis and Fasciola sp.: CT and Parasitological Findings
2
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
We report here a human case probably mixed-infected with Clonorchis sinensis and Fasciola sp. who was diagnosed by computed tomography (CT) scan, serological findings, and/or fecal examination. The patient was a 43-year-old Korean female and was admitted to Kyung Hee University Hospital with the complaints of fever and abdominal pain. On admission, marked eosinophilia was noted in her peripheral blood. CT scan showed specific lesions for clonorchiasis and fascioliasis in the liver, along with lesions suggestive of amebic abscess. Micro-ELISA revealed positive results for the 2helminthic infections. Eggs of C. sinensis and trophozoites of Entamoeba histolytica were observed in the stool. Treatment with praziquantel followed by metronidazole and tinidazole reduced abnormalities in the liver and eosinophilia. This is the first case report of a possible co-infection with 2 kinds of liver flukes in the Republic of Korea.
Abstract
We report here a human case probably mixed-infected with Clonorchis sinensis and Fasciola sp. who was diagnosed by computed tomography (CT) scan, serological findings, and/or fecal examination. The patient was a 43-year-old Korean female and was admitted to Kyung Hee University Hospital with the complaints of fever and abdominal pain. On admission, marked eosinophilia was noted in her peripheral blood. CT scan showed specific lesions for clonorchiasis and fascioliasis in the liver, along with lesions suggestive of amebic abscess. Micro-ELISA revealed positive results for the 2helminthic infections. Eggs of C. sinensis and trophozoites of Entamoeba histolytica were observed in the stool. Treatment with praziquantel followed by metronidazole and tinidazole reduced abnormalities in the liver and eosinophilia. This is the first case report of a possible co-infection with 2 kinds of liver flukes in the Republic of Korea.
참고문헌 (17)
- Keiser J, "Emerging foodborne trematodiasis", Emerg Infect Dis, 11, pp.1507~1514 (2005)
- Arjona R, "Fascioliasis in developed countries: A review of classic and aberrant forms of the disease", Medicine (Baltimore), 74, pp.13~23 (1995)
- Rim HJ, "Clonorchiasis: An update", J Helminthol, 79, pp.269~281 (2005)
- Marcos LA, "Update on hepatobiliary flukes: Fascioliasis, opisthorchiasis and clonorchiasis", Curr Opin Infect Dis, 21, pp.523~530 (2008)
- Choi BI, "Clonorchiasis and cholangiocarcinoma: Etiologic relationship and imaging diagnosis", Clin Microbiol Rev, 17, pp.540~552 (2004)
- 최동일, "Imaging diagnosis of clonorchiasis", The Korean Journal of Parasitology, 45(2), pp.77~85 (2007), 대한기생충학회
- Lim JH, "Biliary parasitic diseases including clonorchiasis, opisthorchiasis and fascioliasis", Abdom Imaging, 33, pp.157~165 (2008)
- Rothenberg ME, "Eosinophilia", N Engl J Med, 338, pp.1592~1600 (1998)
- Weller PF, "Human eosinophils", J Allergy Clin Immunol, 100, pp.283~287 (1997)
- Paik JW, "A case of fascioliasis in the common bile duct", Korean J Gastroenterol, 30, pp.553~558 (1997)
- Aksoy DY, "Infection with Fasciola hepatica", Clin Microbiol Infect, 11, pp.859~861 (2005)
- Gulsen MT, "Fascioliasis: a report of five cases presenting with common bile duct obstruction", Neth J Med, 64, pp.17~19 (2006)
- Aksoy DY, "Fasciola hepatica infection: Clinical and computerized tomographic findings of ten patients", Turk J Gastroenterol, 17, pp.40~45 (2006)
- Harnett W, "The anthelmintic action of praziquantel", Parasitol Today, 4, pp.144~146 (1988)
- Bacq Y, "Successful treatment of acute fascioliasis with bithionol", Hepatology, 14, pp.1066~1069 (1991)
- Keiser J, "Triclabendazole for the treatment of fascioliasis and paragonimiasis", Expert Opin Investig Drugs, 14, pp.1513~1526 (2005)
- Kim CG, "Clinical response to 7-day praziquantel therapy in Fasciola liver abscess", Korean J Infect Dis, 29, pp.417~421 (1997)
