기분장애 환자에서 성별에 따른 일주기유형과 문제음주행동과의 관련
The Relationship between Chronotype and Problematic Drinking according to Gender in Mood Disorder
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Objectives：Some studies have reported that chronotypes, among several factors, could contribute to problematic drinking. However, there is little evidence confirming this relationship between chronotype and problematic drinking based on gender differences in mood disorder. This study is to investigate the difference of the relationship between chronotype and problematic drinking according to gender differences in mood disorder. Methods：Two hundred fifteen patients with mood disorder were recruited. Problematic drinking and chronotypes were assessed by the Alcohol Use Disorder Identification Test in Korea(AUDIT) and the Korean translation of composite scale of morningness(KtCS). We analyzed the correlation between KtCS and AUDIT using Pearson’s correlation, and compared AUDIT scores according to chronotypes classified by KtCS between male and female patients using analysis of variance(ANOVA). Results：There was no significant difference in AUDIT scores between the male and female patients(t=0.91, p= 0.183). In female patients, eveningness had significantly higher AUDIT scores than other chronotypes(F=0.199, p= 0.033). Meanwhile, in male patients, there was no significant difference in AUDIT score among chronotypes(F=0.008, p=0.933). Conclusion：This study suggests that eveningness might be associated with problematic drinking in female patients who suffer from mood disorder. It also suggests that chronotherapeutical treatment might be able to help improve the course in female patients with mood disorder. In the future, a large-scale prospective study is needed to confirm these results.
Abstract
Objectives：Some studies have reported that chronotypes, among several factors, could contribute to problematic drinking. However, there is little evidence confirming this relationship between chronotype and problematic drinking based on gender differences in mood disorder. This study is to investigate the difference of the relationship between chronotype and problematic drinking according to gender differences in mood disorder. Methods：Two hundred fifteen patients with mood disorder were recruited. Problematic drinking and chronotypes were assessed by the Alcohol Use Disorder Identification Test in Korea(AUDIT) and the Korean translation of composite scale of morningness(KtCS). We analyzed the correlation between KtCS and AUDIT using Pearson’s correlation, and compared AUDIT scores according to chronotypes classified by KtCS between male and female patients using analysis of variance(ANOVA). Results：There was no significant difference in AUDIT scores between the male and female patients(t=0.91, p= 0.183). In female patients, eveningness had significantly higher AUDIT scores than other chronotypes(F=0.199, p= 0.033). Meanwhile, in male patients, there was no significant difference in AUDIT score among chronotypes(F=0.008, p=0.933). Conclusion：This study suggests that eveningness might be associated with problematic drinking in female patients who suffer from mood disorder. It also suggests that chronotherapeutical treatment might be able to help improve the course in female patients with mood disorder. In the future, a large-scale prospective study is needed to confirm these results.
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