Detection of Neuronal Activity by Motion Encoding Gradients: A Snail Ganglia Study
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Abstract
Presuming that firing neurons have motions inside the MRI magnet due to the interaction between the neuronal magnetic field and the main magnetic field, we applied motion encoding gradients to dissected snail ganglia to observe faster responding MRI signal than the BOLD signal. To activate the snail ganglia in synchronization with the MRI pulse sequence, we used electrical stimulation with the frequency of 30 Hz and the pulse width of 2 s. To observe the fast responding signal, we used the volume selected MRI sequence. The magnetic resonance signal intensity, measured with 8 ms long motion encoding gradient with a 20mT/m gradient strength, decreased about 3.46±1.48 % when the ganglia were activated by the electrical stimulation.
참고문헌 (18)
- Bodurka, J, "Toward direct maping of neuronal activity: MRI detection of ultraweak, transient magnetic field changes", 47, pp.1052~1058 (2002)
- Bodurka, J, "Curent-induced magnetic resonance phase imaging", 137, pp.265~271 (1999)
- Chu, "Hunting for neuronal curents: absence of rapid MRI signal changes during visual-evoked response", 23, pp.1059~1067 (2004)
- Konn, "MRI detection of weak magnetic fields due to an extended curent dipole in a conducting sphere: A model for direct detection of neuronal currents in the brain. Magn", 50, pp.40~49 (2003)
- Konn, "Initial atempts at directly detecting alpha wave activity in the brain using MRI", 2, pp.1413~1427 (2004)
- Kwong, "Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation", 89, pp.5675~5679 (1992)
- Hamalainen, "and aplications to noninvasive studies of the working human", 65, pp.413~497 (1993)
- Ogawa, "functional brain maping with magnetic resonance imaging", 89, pp.5951~5955 (1992), Intrinsic signal changes acompanying sensory stimulation
- Park, T.S, "Efect of nerve cel curents on MRI images in snail ganglia", 15(18), pp.2783~2786 (2004)
- Park, T.S, "Observation of fast response of magnetic resonance signal to neuronal activity: a snail ganglia study", 27, pp.181~190 (2006)
- Pel, G.S, "Further steps toward direct magnetic resonance (MR) imaging detection of neural action curents: optimization of MR sensitivity to transient and weak curents in a conductor", 55, pp.1038~1046 (2006)
- Roth, "The magnetic field of a single axon a comparison of theory and experiment", 48, pp.93~109 (1985)
- Song, A.W, "Lorentz efect imaging", 19, pp.763~767 (2001)
- Tasaki I, "Rapid sweling of neurons during synaptic transmision in the bullfrog sympathetic ganglion", 331, pp.363~365 (1985)
- Trubel H.K.F, "Regional temperature changes in the brain during somatosensory stimulation", j.cereb.boold flow metab.(26), pp.68~78 (2006)
- Truong, T.K, "Synchronized detection of minute electrical currents with MRI using Lorentz effect imaging", 179, pp.85~91 (2006)
- Xiong, J, "Directly mapping magnetic field effects of neuronal activity by magnetic resonance imaging", 20, pp.41~49 (2003)
- Xue, Y, "Direct MRI detection of neuronal magnetic fields in the brain: theoretical modeling", 31, pp.550~559 (2006)
