Fecal Microbiota Transplantation beyond Clostridioides Difficile Infection
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초록
Obesity is becoming increasingly prevalent worldwide, and its metabolic sequelae lead to a significant burden on healthcareresources. Options for the management of obesity include lifestyle modification, pharmacological treatment, surgery, and endoscopicWith advancing analytical methods for gut microbes, many studies have been conducted, revealing that gut microbes cause variousdiseases, including gastrointestinal and non-gastrointestinal diseases. Accordingly, studies have been actively conducted to analyzethe effects on the prevention and treatment of these diseases through changes in intestinal microbes and control of dysbiosis. Fecalmicrobiota transplantation (FMT) is an effort and is currently being applied to Clostridioides difficile treatment in Korea. Manystudies have demonstrated the application of FMT in inflammatory bowel disease, irritable bowel syndrome, non-alcoholic fattyliver disease, metabolic syndrome, obesity, and diabetes. With further studies and accumulation of evidence, FMT could help treatpresently untreatable diseases in clinical practice.
Abstract
Obesity is becoming increasingly prevalent worldwide, and its metabolic sequelae lead to a significant burden on healthcareresources. Options for the management of obesity include lifestyle modification, pharmacological treatment, surgery, and endoscopicWith advancing analytical methods for gut microbes, many studies have been conducted, revealing that gut microbes cause variousdiseases, including gastrointestinal and non-gastrointestinal diseases. Accordingly, studies have been actively conducted to analyzethe effects on the prevention and treatment of these diseases through changes in intestinal microbes and control of dysbiosis. Fecalmicrobiota transplantation (FMT) is an effort and is currently being applied to Clostridioides difficile treatment in Korea. Manystudies have demonstrated the application of FMT in inflammatory bowel disease, irritable bowel syndrome, non-alcoholic fattyliver disease, metabolic syndrome, obesity, and diabetes. With further studies and accumulation of evidence, FMT could help treatpresently untreatable diseases in clinical practice.
참고문헌 (32)
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