아연(Zn) 첨가사료의 투여에 따른 돌돔, Oplegnathus fasciatus의 항산화효소활성의 변화
Changes in the antioxidant enzyme activities of rock bream Oplegnathus fasciatus administrated with Zn-supplemented diets
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
우리나라의 주요 해산양식어종인 돌돔, Oplegnathus fasciatus을 대상으로 30, 60, 120 및 240 mg/kg의 아연을40일 동안 경구 투여에 따른 아가미와 간의 항산화효소활성의 변화를 검토하였다. 돌돔 간의 superoxide dismutase(SOD) 활성은30~240 mg/kg 아연농도, glutathione peroxidase (GPx)활성은 30~120 mg/kg의 아연농도에서 유의적으로증가하였다. 돌돔 아가미의 SOD 및 Glutathione(GSH)활성은 120 및 240 mg/kg 아연농도, GPx활성은60~240 mg/kg의 아연농도에서 유의한 증가가 관찰되었다.
Abstract
The objective of this study was to investigate the antioxidant enzyme (superoxide dismutase, SOD; glutathione, GSH;glutathione peroxidase, GPx) activities in liver and gill of rock bream, Oplegnathus fasciatus fed the experimental diets for 40 days. The experimental diets were prepared by adding with 30, 60 120 and 240 mg/kg to a commercial diet. In the liver, there were significant increases in SOD at 30∼240 mg/kg. GPx activities of liver also were significantly increased at 30∼120 mg/kg. The increased activities of SOD and GSH in the gills were observed in the 120 and 240 mg/kg, hence, GPx activity of gill exposed to lower concentrations of zinc (60∼240 mg/kg) showed significant augmentation.
참고문헌 (21)
- Amira, A.S., "Effet of dietary zinc on lipid peroxidation, glutathione, protein thiols levels and superoxide dismutase activity in rat tissues", Int. J. Cell. Biol, 27, pp.89~95 (1995)
- Bray, T.M., "Physiological role zinc as an antitoxidant", Free Radic. Biol. Med, 8, pp.281~ (1990)
- Dallinger, R., "The importance of contaminated food for the uptake of heavy metals by rainbow trout (Salmo gairdneri): a field study", Oecologia, 67, pp.82~89 (1985)
- Friverg, I., "Mercury in the environment" (1972), CRS Press, ISI
- Geeta, S., "Effect of ethanol on Cd-induced lipid peroxidation and antioxidant enzymes in rat liver", Biochem. Pharmacol, 42, pp.S9~S16 (1991)
- Gropper, S.S., "Advanced Nutrition and Human Metabolism. 4th ed", pp.417~445 (2005), Thomson Wadsworth
- Hill, C.H., "Chemical parameters in the study of in vivo and in vitro interactions of transition element", Ged. Proc, 29, pp.14~74 (1970)
- NRC, "Nutrient Requirements of fish", pp.114~ (1993), National Acad. Press
- Ogino, C., "Requirement of rainbow trout for dietary zinc", Bull. Jpn. Soc. Sci. Fish, 42, pp.793~799 (1978)
- Ogino, C., "Requirement of carp for dietary zinc", Bull. Jpn. Soc. Sci. Fish, 46, pp.455~458 (1979)
- Samman, S., "Dietary versus cellular zinc : The antioxidant paradox", Free Radic. Biol. Med, 14, pp.95~96 (1993)
- Shils, M.E., "Modern Nutrition in Health and Disease. 10th ed", pp.271~285 (2005), Lippincott Williams & Wilkins
- Singh, K.P., "Effect of zinc on immune functions and host resistance against infection and tumor challenge", Immuno-pharmacol. Immunotoxicol, 14, pp.813~840 (1992)
- Sorensen, E.M.B., "Metal Poisoning in Fish" (1991), CRC
- Spilttgerber, A.G., "Inhibition of glutathione peroxidase by cadmium and other metal ions", Arch. Biochem. Biophys, 197(2), pp.534~542 (1979)
- Taylor, C.G., "Effects of hyperoxia on oxygen free radical defense enzymes in the lung of Zn-deficient rats", J. Nutr, 121(4), pp.460~466 (1991)
- Zhou, Y., "Structural studies on metal-serum albumin Ⅳ. The interaction of Zn(Ⅱ), Cd(Ⅱ) and Hg(Ⅱ) with HSA and BSA", Biophys. Chem, 42(2), pp.201~211 (1992)
- 김현숙, "아연 수준이 비만쥐의 당대사와 혈청 아연, 마그네슘, 크롬 함량에 미치는 영향", 한국식품영양과학회지, 38(9), pp.1174~1178 (2009), 한국식품영양과학회
- 송미영, "아연 보충이 젊은 여성의 혈청 콜레스테롤 농도에 미치는 영향", 한국영양학회지, 23, pp.237~247 (1990)
- 이상민, "사료의 P, Ca, Zn, Mg, Fe, K, Mn과 Se이 조피볼락의 성장 및 체성분에 미치는 영향", J. Kor. Fish. Soc, 31(2), pp.245~251 (1998)
- 조수열, "식이성 아연 수준이 카드뮴 중독에 미치는 영향", J. Kor. Soc. Food. Sci. Nutr, 23(4), pp.574~580 (1994)