화재관련 사망자들의 혈액중 독성물질의 농도 및 검출약물
Concentrations of Toxic Substances and Drugs Detected in Blood of Fire Related Fatalities
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2013년 11월~2015년 5월까지 국립과학수사연구원에 의뢰된 화재관련 사망자 120명의 혈액에서 독성물질(CO-Hb, cyanide 및 에틸알코올)의 농도와 검출되는 약물의 유형에 대하여 분석하였다. 화재사에서 검출된 청산(HCN)의 농도는 심장혈액에서 0~6.5 mg/L 및 말초혈액에서 0~2.9 mg/L이었고, 심장혈액에서 CO-Hb의 농도는 0~86% 그리고 에틸알코올의 농도는 0~0.39%이었다. 또한, 다빈도로 검출된 약물은 chlorpheniramine, zolpidem, diazepam 및 midazolam이었으며 이들은 모두 수면 효과와 관련된 약물들이다. 본 연구에서 분석한 화재관련 사망자의 혈액에서 다빈도로 검출된 독성 물질들의 농도범위는 CO-Hb 41~80%, cyanide 0~1 mg/L 및 에틸알코올 0~0.50%이었다. 결론적으로, 화재 사망자의 사인 결정 시, CO-Hb와 cyanide의 농도, 에탄올 검출여부 및 수면야기 약물의 검출여부 등에 대하여 종합적인 검토가 필요하다.
Abstract
The author analyzed the concentrations of toxic substances of cyanide, CO-Hb, ethanol, and drugs detected in the blood of autopsy specimens, 120 cases of the fire related fatalities (FRF), which were requested to National Forensic Service during from 2013. 11 to 2015. 5. The concentration ranges of detected toxic substances in FRF were 0~6.5 mg/L as cyanide in cardiac blood and 0~2.9 mg/L in peripheral blood, 0~86% as CO-Hb, and 0~0.39% as ethyl alcohol in cardiac blood. Frequently detected drugs in FRF include chlorpheniramine, zolpidem, diazepam and midazolam, they are related to effects of sleeping. The concentration ranges of most frequently detected toxic substances in the blood of FRF were 41~80% as CO-Hb, 0~1 mg/ L as cyanide, and 0~0.50% as ethyl alcohol. In conclusion, the integrated evaluation of toxic substances of CO-Hb, cyanide ion and ethyl alcohol as well as sleeping drugs detected, should be conducted for the decision of the cause of fire deaths.
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