자주광대나물 메탄올 추출물과 분획물의 항산화 및 항염증 활성
Antioxidant and Anti-inflammatory Activities of Methanolic Extract and its Fractions of Lamium purpureum L
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Lamium purpureum is widely distributed in Europe, Africa, and Asia based on its rapid reproduction and high survival rate, and is also found in domestic pastures, gardens, and cultivated land. In this study, L. purpureum was extracted with methanol and fractionated into hexane, ethyl acetate, and butanol, with experiments conducted on total phenol, total flavonoid, antioxidant, NO production inhibitory activity, and cytotoxicity. The total phenol, total flavonoid, and antioxidant activity of L. purpureum are shown in the order of butanol fraction, methanol extract, ethyl acetate fraction, water fraction, and hexane fraction. The NO production inhibitory activity showed the highest inhibitory effect in the ethyl acetate fraction, while 4.2% inhibitory activity was confirmed in the butanol fraction for cytotoxicity. Cytotoxicity was not observed in other samples. Through this experiment, the physiological activity of L. purpureum was verified, and it is expected to become primary data that can be used in future studies.
Abstract
Lamium purpureum is widely distributed in Europe, Africa, and Asia based on its rapid reproduction and high survival rate, and is also found in domestic pastures, gardens, and cultivated land. In this study, L. purpureum was extracted with methanol and fractionated into hexane, ethyl acetate, and butanol, with experiments conducted on total phenol, total flavonoid, antioxidant, NO production inhibitory activity, and cytotoxicity. The total phenol, total flavonoid, and antioxidant activity of L. purpureum are shown in the order of butanol fraction, methanol extract, ethyl acetate fraction, water fraction, and hexane fraction. The NO production inhibitory activity showed the highest inhibitory effect in the ethyl acetate fraction, while 4.2% inhibitory activity was confirmed in the butanol fraction for cytotoxicity. Cytotoxicity was not observed in other samples. Through this experiment, the physiological activity of L. purpureum was verified, and it is expected to become primary data that can be used in future studies.
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